1126639-74-4

Basic information

• Product Name: C₂₃H₂₃NO₃S₂
• CAS NO: 1126639-74-4
• Molecular Weight: 425.573
• Mol File: 1126639-74-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₃H₂₃NO₃S₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₃H₂₃NO₃S₂(1126639-74-4)
• EPA Substance Registry System: C₂₃H₂₃NO₃S₂(1126639-74-4)

Safety Data

• Hazardous Substances Data: 1126639-74-4(Hazardous Substances Data)

Upstream product

• 34250-61-8 2-amino-5-ethoxybenzenethiol 
• 74441-58-0 3-(3,4-dimethoxyphenyl)-1-(thiophen-2-yl)-2-propen-1-one 

Relevant articles and documents

Syntheses of 1,5-benzothiazepines: Part-XXXIV. Syntheses and antimicrobial studies of 8-substituted-2,5-dihydro-2-(4-methoxyphenyl/3,4-dimethoxyphenyl)-4- (2-thienyl)-1,5-benzothiazepines

Reactions of the 5-substituted-2-aminobenzenethiols 4a-f with the α,β-unsaturated heterocyclic ketones 3a,b were carried out in dry ethanol saturated with dry HCl gas. The products 5a-1 were characterized by microestimations for C, H, N, S and IR, 1H NMR, 13C NMR, 19F NMR and mass spectral studies. The synthesized compounds were screened for antimicrobial activity against the bacteria, Staphylococcus aureus and Pseudomonas aeruginosa and the fungus, Candida albicans. All the compounds showed moderate activity against the bacteria Staphylococcus aureus and Pseudomonas aeruginosa with reference to standard drugs, gatifloxin and natilmicin but showed good activity against the fungus, Candida albicans with reference drug fluconazole. The maximum antifungal activity has been shown by the compound 5k having maximum number of methoxyl groups and 5g and 5a having fluoro in addition to methoxyl groups.