74441-58-0

Basic information

• Product Name: 1-(2-THIENYL)-3-(3,4-DIMETHOXYPHENYL)-2-PROPEN-1-ONE
• Synonyms: 1-(2-THIENYL)-3-(3,4-DIMETHOXYPHENYL)-2-PROPEN-1-ONE
• CAS NO: 74441-58-0
• Molecular Formula: C₁₅H₁₄O₃S
• Molecular Weight: 0
• Mol File: 74441-58-0.mol
• Article Data: 13

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(2-THIENYL)-3-(3,4-DIMETHOXYPHENYL)-2-PROPEN-1-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-THIENYL)-3-(3,4-DIMETHOXYPHENYL)-2-PROPEN-1-ONE(74441-58-0)
• EPA Substance Registry System: 1-(2-THIENYL)-3-(3,4-DIMETHOXYPHENYL)-2-PROPEN-1-ONE(74441-58-0)

Safety Data

• Hazardous Substances Data: 74441-58-0(Hazardous Substances Data)

Usage

Source

Natural product isolated from the rhizomes of Curcuma phaeocaulis, a perennial herb from the family Zingiberaceae

Pharmacological activities

Anti-inflammatory
Antioxidant
Anti-tumor

Neuroprotective agent

Potential treatment for Alzheimer's disease

Anti-microbial activity

Potential applications in the development of new drugs for infectious diseases

Chemical structure

Unique chemical structure that contributes to its diverse biological activities

Research value

Valuable compound for further research and potential therapeutic development

Upstream product

• 88-15-3 2-Acetylthiophene 
• 120-14-9 3,4-dimethoxy-benzaldehyde 

Downstream Products

• 152432-17-2 1-acetyl-5-(3,4-dimethoxyphenyl)-3-(thienyl)-2-pyrazoline 
• 137444-74-7 4-(3,4-dimethoxyphenyl)-2-methoxy-6-(2-thienyl)nicotinonitrile 
• 137444-79-2 2-ethoxy-4-(3,4-dimethoxyphenyl)-6-(2-thienyl)nicotinonitrile 
• 1126639-70-0 C₂₁H₁₈ClNO₂S₂ 
• 1126639-74-4 C₂₃H₂₃NO₃S₂ 
• 1126639-72-2 2,5-dihydro-8-methyl-2-(3,4-dimethoxyphenyl)-4-(2-thienyl)-1,5-benzothiazepine 
• 1126639-69-7 8-fluoro-2,5-dihydro-2-(3,4-dimethoxyphenyl)-4-(2-thienyl)-1,5-benzothiazepine 
• 1126639-71-1 C₂₁H₁₈BrNO₂S₂ 
• 1126639-73-3 C₂₂H₂₁NO₃S₂ 
• 267885-40-5 C₁₃H₁₀O₃S 

Relevant articles and documents

Convenient synthesis and molecular docking of novel pyrido [2,3-d] pyrimidines as potent antimicrobial candidates

New 3-(3,4-dimethoxyphenyl)-1-(thiophen-2-yl) prop-2-en-1-one has been designed as a starting compound to synthesis a novel series of substituted pyrido[2,3-d]pyrimidine system incorporated to different Schiff's bases and enamine derivatives as potent ant

Chalcone derivatives targeting mitosis: synthesis, evaluation of antitumor activity and lipophilicity

This study describes the synthesis of a series of chalcones, including pyrazole and α,β-epoxide derivatives, and evaluation of their cell growth inhibitory activity in three human tumor cell lines, as well as their lipophilicity using liposomes as a biomi

Synthesis of lignan conjugates via cyclopropanation: Antimicrobial and antioxidant studies

Ethyl 2-(4-methoxyphenyl)-3-(thiophene-2-carbonyl)cyclopropanecarboxylates 2(a–f) and ethyl 4-aryl-7-oxo-4,5,6,7-tetrahydrobenzo[b]thiophene-5-carboxylates 4(a–f) were synthesized by simple procedure. The synthesized new compounds were screened in vitro for their antimicrobial and antioxidant activities. The compounds 2b and 4f showed excellent antibacterial activity; while 2b and 4f showed remarkable antifungal properties. The results of antioxidant activity studies revealed that compounds 4b and 4f manifested profound antioxidant potential. The docking studies were done for the final compounds. The ADME result indicates that all these molecules possess pharmaceutical properties in the range of 95% of drugs.