112791-04-5

Basic information

• Product Name: (4S,5R)-(+)-1,5-DIMETHYL-4-PHENYL-2-IMIDAZOLIDINONE
• Synonyms: (4S,5R)-(+)-1,5-DIMETHYL-4-PHENYL-2-IMIDAZOLIDINONE;(4S 5R)-1 5-DIMETHYL-4-PHENYL-2-IMIDAZOLIDONE;(4S 5R)-(+)-1 5-DIMETHYL-4-PHENYL- &;(4S,5R)-(+)-1,5-DiMethyl-4-phenyl-2-iMidazolidinone,97%
• CAS NO: 112791-04-5
• Molecular Formula: C₁₁H₁₄N₂O
• Molecular Weight: 190.24
• Product Categories: Chiral Building Blocks;Heterocyclic Building Blocks;Imidazolines/Imidazolidines
• Mol File: 112791-04-5.mol
• Article Data: 6

Chemical Properties

• Melting Point: 173-176 °C(lit.)
• Boiling Point: 335.9°Cat760mmHg
• Flash Point: 156.9°C
• Appearance: /
• Density: 1.077g/cm³
• Vapor Pressure: 0.000116mmHg at 25°C
• Refractive Index: 1.532
• PKA: 13.70±0.60(Predicted)
• BRN: 4905832
• CAS DataBase Reference: (4S,5R)-(+)-1,5-DIMETHYL-4-PHENYL-2-IMIDAZOLIDINONE(CAS DataBase Reference)
• NIST Chemistry Reference: (4S,5R)-(+)-1,5-DIMETHYL-4-PHENYL-2-IMIDAZOLIDINONE(112791-04-5)
• EPA Substance Registry System: (4S,5R)-(+)-1,5-DIMETHYL-4-PHENYL-2-IMIDAZOLIDINONE(112791-04-5)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 3
• Hazardous Substances Data: 112791-04-5(Hazardous Substances Data)

Usage

General Description

(4S,5R)-(+)-1,5-DIMETHYL-4-PHENYL-2-IMIDAZOLIDINONE is a chemical compound with a specific stereochemical configuration. It is a cyclic imidazolidinone containing a phenyl group and two methyl groups. (4S,5R)-(+)-1,5-DIMETHYL-4-PHENYL-2-IMIDAZOLIDINONE is used in organic synthesis as a chiral auxiliary and as a catalyst in various reactions. Its specific stereochemical configuration makes it a valuable tool in the preparation of chiral compounds and in the study of asymmetric synthesis. (4S,5R)-(+)-1,5-DIMETHYL-4-PHENYL-2-IMIDAZOLIDINONE is also used in pharmaceutical research and development for the synthesis of biologically active molecules and drug candidates.

InChI:InChI=1/C11H14N2O/c1-8-10(12-11(14)13(8)2)9-6-4-3-5-7-9/h3-8,10H,1-2H3,(H,12,14)/t8-,10-/m1/s1

Upstream product

• 4785-79-9 1,3-dihydro-1,5-dimethyl-4-phenyl-2H-imidazol-2-one 
• 90-81-3 ephedrine 
• 57-13-6 urea 
• 50-98-6 ephedrine hydrochloride 
• 25394-33-6 (+)-2-chloro-1,N-dimethyl-2-phenylethylamine 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 259540-46-0 (2R,3R)-1,4-bis((4R,5S)-3,4-dimethyl-2-oxo-5-phenylimidazolidinyl)-2,3-bis[(3-methoxyphenyl)methyl]butane-1,4-dione 
• 100-39-0 benzyl bromide 
• 24221-86-1 (+)-(1S,2R)-ephedrine hydrochloride 

Downstream Products

• 151062-79-2 (4R,5S)-1-((E)-Hex-2-enoyl)-3,4-dimethyl-5-phenyl-imidazolidin-2-one 
• 112791-05-6 (4S,5R)-1,5-dimethyl-4-phenyl-3-(3'-methyl-2'-butenoyl)imidazolidin-2-one 
• 151213-79-5 (4R,5S,E)-1-but-2-enoyl-3,4-dimethyl-5-phenylimidazolidin-2-one 
• 123394-73-0 (4S,5R)-1,5-dimethyl-4-phenyl-3-benzyloxyacetylimidazolidin-2-one 
• 112791-07-8 (4S,5R)-1,5-dimethyl-4-phenyl-3-propanoylimidazolidin-2-one 
• 143359-26-6 (4R,5S)-1-acetyl-3,4-dimethyl-5-phenyl-2-imidazolidinone 
• 143359-25-5 (4R,5S)-(+)-(2'-chloroacetyl)-3,4-dimethyl-5-phenyl-2-imidazolidinone 
• 143396-14-9 (4R,5S)-3,4-dimethyl-5-phenyl-1-(3-phenylpropanoyl)-2-imidazolidinone 
• 169125-10-4 (4S,5R)-1,5-dimethyl-4-phenyl-3-trimethylsilyl-2-imidazolidinone 
• 182511-11-1 (4R,5S)-1-((E)-3-Biphenyl-4-yl-acryloyl)-3,4-dimethyl-5-phenyl-imidazolidin-2-one 
• 182511-12-2 (4R,5S)-1-[(E)-3-(4'-Bromo-biphenyl-4-yl)-acryloyl]-3,4-dimethyl-5-phenyl-imidazolidin-2-one 
• 157659-19-3 (4R,5S)-1-cinnamoyl-3,4-dimethyl-5-phenylimidazolidin-2-one 
• 943253-14-3 C₁₄H₁₆ON₂ 
• 943253-15-4 C₃₆H₄₄N₂O₃Si 

Relevant articles and documents

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Highly diastereoselective alkylation of vicinal dianions of chiral succinic acid derivatives: A new general strategy to (R)-β-arylmethyl-γ- butyrolactones

The vicinal dianions derived from chiral succinic acid derivatives, 1,4-bis[(4R,5S)-3,4-dimethyl-2-oxo-5-phenylimidazolidin-1-yl]butane-1,4-dione and 1,4-bis[(4S,5R)-3,4-dimethyl-2-oxo-5-phenylimidazolidin-1-yl]butane-1,4- dione react with arylmethyl bromides with high diastereo- and regio-selectivity to provide the corresponding chiral α-arylmethylated succinic acid derivatives; the (R)-products are converted into (R)-β-arylmethyl-γ- butyrolactones and (R)-α-arylmethyl-γ-butyrolactones.

Asymmetric induction in the electrochemical cross-coupling of aryl halides with α-chloropropionic acid derivatives catalyzed by nickel complexes

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