1128-10-5

Basic information

• Product Name: Cyclobutene-1,2-dicarboxylic acid dimethyl ester
• Synonyms: 1-Cyclobutene-1,2-dicarboxylic acid dimethyl ester;Cyclobutene-1,2-dicarboxylic acid dimethyl ester;diMethyl cyclobut-1-ene-1,2-dicarboxylate;1,2-Bis(methoxycarbonyl)cyclobut-1-ene;1,2-Dicarbomethoxycyclobutene;1,2-Dimethyl 1-cyclobutene-1,2-dicarboxylate;Dimethyl 1-cyclobutene-1,2-dicarboxylate;Dimethyl cyclobutene-1,2-dicarboxylate
• CAS NO: 1128-10-5
• Molecular Formula: C₈H₁₀O₄
• Molecular Weight: 170.16
• Mol File: 1128-10-5.mol
• Article Data: 2

Chemical Properties

• Melting Point: 45-46℃
• Boiling Point: 60-68℃ (0.2 Torr)
• Flash Point: 104.6°C
• Appearance: /
• Density: 1.255g/cm³
• Vapor Pressure: 0.109mmHg at 25°C
• Refractive Index: 1.501
• Storage Temp.: 2-8°C
• CAS DataBase Reference: Cyclobutene-1,2-dicarboxylic acid dimethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclobutene-1,2-dicarboxylic acid dimethyl ester(1128-10-5)
• EPA Substance Registry System: Cyclobutene-1,2-dicarboxylic acid dimethyl ester(1128-10-5)

Safety Data

• Hazardous Substances Data: 1128-10-5(Hazardous Substances Data)

Usage

Chemical Properties

98%

InChI:InChI=1/C8H10O4/c1-11-7(9)5-3-4-6(5)8(10)12-2/h3-4H2,1-2H3

Upstream product

• 10359-27-0 1,2-dibromo-cyclobutane-1r,2c-dicarboxylic acid dimethyl ester 
• 67-56-1 methanol 
• 52477-78-8 cyclobut-1-ene-1,2-dicarbonyl chloride 
• 868-72-4 dimethyl 2,5-dibromohexanedioate 
• 74-88-4 methyl iodide 
• 3716-97-0 1,2-dicyanocyclobutene 
• 3396-17-6 trans-1,2-dicyanocyclobutane 
• 3496-67-1 1,2-Dichlor-cyclobutan-1,2-dicarbonitril 
• 16508-05-7 Cyclobuten-1,2-dicarbonsaeure 
• 124-04-9 Adipic acid 
• 4462-96-8 cis-1,2-cyclobutane dicarboxylic anhydride 
• 3246-91-1 (+/-)-1,2-dibromo-cyclobutane-1r,2t-dicarboxylic acid dimethyl ester 

Downstream Products

• 16508-05-7 Cyclobuten-1,2-dicarbonsaeure 
• 449-46-7 2-(4-fluorophenyl)quinoxaline 
• 131225-97-3 6-(4-Fluoro-phenyl)-11-phenyl-8,9-dihydro-azepino[1,2-a]quinoxaline-7,10-dicarboxylic acid dimethyl ester 
• 131225-91-7 6-(4-Fluoro-phenyl)-9-phenyl-7,8-dihydro-6aH-5,9a-diaza-cyclobuta[3,4]cyclopenta[1,2-a]naphthalene-6b,8a-dicarboxylic acid dimethyl ester 
• 131225-98-4 6-(4-Bromo-phenyl)-11-phenyl-8,9-dihydro-azepino[1,2-a]quinoxaline-7,10-dicarboxylic acid dimethyl ester 
• 5021-45-4 2-(4-bromophenyl)quinoxaline 
• 131225-94-0 11-(4-Fluoro-phenyl)-6-phenyl-8,9-dihydro-azepino[1,2-a]quinoxaline-7,10-dicarboxylic acid dimethyl ester 
• 131225-88-2 9-(4-Fluoro-phenyl)-6-phenyl-7,8-dihydro-6aH-5,9a-diaza-cyclobuta[3,4]cyclopenta[1,2-a]naphthalene-6b,8a-dicarboxylic acid dimethyl ester 
• 131225-95-1 11-(4-Chloro-phenyl)-6-phenyl-8,9-dihydro-azepino[1,2-a]quinoxaline-7,10-dicarboxylic acid dimethyl ester 
• 131225-89-3 9-(4-Chloro-phenyl)-6-phenyl-7,8-dihydro-6aH-5,9a-diaza-cyclobuta[3,4]cyclopenta[1,2-a]naphthalene-6b,8a-dicarboxylic acid dimethyl ester 
• 5021-43-2 2-phenylquinoxaline 

Relevant articles and documents

Synthetic method of alicyclic diester

The invention discloses a synthetic method of alicyclic diester. The synthetic method comprises the following steps: enabling diacid comprising a multi-carbon lipid chain end group or diester containing a multi-carbon lipid chain end group to react with a first halogenation reagent, after the reaction is completed, adding a second halogenation reagent into a reaction product, after the reaction iscompleted, re-esterifying, and obtaining the di-ester of di-halogenation; adding the di-ester of the di-halogenation into an organic solvent, adding alkali to perform the reaction, after the reactionis completed, adding acid to perform the neutralization, and obtaining annular di-ester; and performing the reduction reaction for the annular di-ester, and obtaining the alicyclic diester. By adopting the synthetic method, a novel reaction path is developed, and the direct-chain end-group diacid or diester is used as a raw material to prepare the alicyclic diester by virtue of bromination reaction, ring-closing reaction and the reduction reaction. The initial raw material is low in cost, the process is simple, the reaction condition requirement is low, the safety is good, the product yield and purity are high, and the mass production is easy to realize. Moreover, the diester of a three-membered ring to an eighteen-membered ring can be prepared by utilizing the synthetic method of the invention.