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1128105-72-5

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1128105-72-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1128105-72-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,2,8,1,0 and 5 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1128105-72:
(9*1)+(8*1)+(7*2)+(6*8)+(5*1)+(4*0)+(3*5)+(2*7)+(1*2)=115
115 % 10 = 5
So 1128105-72-5 is a valid CAS Registry Number.

1128105-72-5Relevant articles and documents

Discovery of a potent pyrazolopyridine series of γ-secretase modulators

Qin, Jun,Zhou, Wei,Huang, Xianhai,Dhondi, Pawan,Palani, Anandan,Aslanian, Robert,Zhu, Zhaoning,Greenlee, William,Cohen-Williams, Mary,Jones, Nicholas,Hyde, Lynn,Zhang, Lili

, p. 471 - 476 (2011/08/22)

The synthesis and structure-activity relationship of a novel series of pyrazolopyridines are reported. These compounds represent a new class of γ-secretase modulators that demonstrate good in vitro potency in inhibiting Aβ42 production. Example

GAMMA SECRETASE MODULATORS

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Page/Page column 434, (2009/04/25)

This invention provides novel compounds that are modulators of gamma secretase. The compounds have the formula (I). Also disclosed are methods of modulating gamma secretase activity and methods of treating Alzheimer's Disease using the compounds of formul

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