113001-98-2Relevant articles and documents
INGENOL-3-ACYLATES I
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Page/Page column 41, (2012/07/13)
The invention relates to compounds of general formula (I) wherein R is (C1-C7)alkyl, (C2-C7)alkenyl or (C2-C7)alkynyl; wherein R is substituted with R1; and pharmaceutically acceptable salt
SYNTHESIS OF 1,3-DIAZASPIROUNDECANES AND 1-THIA-3-AZASPIROUNDEC-2-ENES BY REACTION OF 2-CYANOCYCLOHEXYLIDENEACETYL ISOTHIOCYANATE WITH AMINES AND SODIUM HYDROGEN SULFIDE
Dzurilla, Milan,Forgac, Ondrej,Kutschy, Peter,Kristian, Pavol,Koscik, Dusan,Imrich, Jan
, p. 989 - 994 (2007/10/02)
2-Cyanocyclohexylideneacetyl isothiocyanate (II) reacts with sodium hydrogen sulfide to give 1-thia-3-azaspiroundecane.Reaction of II with secondary amines afforded 1-thia-3-azaspiroundec-2-enes whereas primary aromatic amines gave 1,3-diazaspir