113002-08-7Relevant articles and documents
SYNTHESIS OF 1,3-DIAZASPIROUNDECANES AND 1-THIA-3-AZASPIROUNDEC-2-ENES BY REACTION OF 2-CYANOCYCLOHEXYLIDENEACETYL ISOTHIOCYANATE WITH AMINES AND SODIUM HYDROGEN SULFIDE
Dzurilla, Milan,Forgac, Ondrej,Kutschy, Peter,Kristian, Pavol,Koscik, Dusan,Imrich, Jan
, p. 989 - 994 (2007/10/02)
2-Cyanocyclohexylideneacetyl isothiocyanate (II) reacts with sodium hydrogen sulfide to give 1-thia-3-azaspiroundecane.Reaction of II with secondary amines afforded 1-thia-3-azaspiroundec-2-enes whereas primary aromatic amines gave 1,3-diazaspir