1132641-31-6

Basic information

• Product Name: methyl 2-(((tertbutoxycarbonyl)oxy)(4-fluorophenyl)methyl)acrylate
• Synonyms: methyl 2-(((tertbutoxycarbonyl)oxy)(4-fluorophenyl)methyl)acrylate
• CAS NO: 1132641-31-6
• Molecular Weight: 310.322
• Mol File: 1132641-31-6.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: methyl 2-(((tertbutoxycarbonyl)oxy)(4-fluorophenyl)methyl)acrylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-(((tertbutoxycarbonyl)oxy)(4-fluorophenyl)methyl)acrylate(1132641-31-6)
• EPA Substance Registry System: methyl 2-(((tertbutoxycarbonyl)oxy)(4-fluorophenyl)methyl)acrylate(1132641-31-6)

Safety Data

• Hazardous Substances Data: 1132641-31-6(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 353506-65-7 methyl 3-(4-fluorophenyl)-3-hydroxy-2-methylenepropanoate 
• 459-57-4 4-fluorobenzaldehyde 

Downstream Products

• 1132641-42-9 C₂₃H₁₇FN₂O₂S 
• 1236226-89-3 (R)-methyl 2-((diethylphosphoryl)(4-fluorophenyl)methyl)acrylate 
• 1238053-85-4 (S)-(+)-methyl 3-hydroxy-2-methylene-3-(4-fluorophenyl)propanoate 
• 1341212-13-2 (R)-methyl 3-hydroxy-2-methylene-3-(4-fluorophenyl)propanoate 
• 353506-65-7 methyl 3-(4-fluorophenyl)-3-hydroxy-2-methylenepropanoate 
• 1330067-03-2 (R)-methyl 2-((N-allyl-4-methylphenylsulfonamido)(4-fluorophenyl)-methyl)acrylate 
• 1334856-68-6 (S,E)-methyl 2-benzyl-4-(4-fluorobenzylidene)-5-oxopyrrolidine-2-carboxylate 

Relevant articles and documents

Umpolung of o-Hydroxyaryl Azomethine Ylides: Entry to Functionalized ?-Aminobutyric Acid under Phosphine Catalysis

A phosphine-catalyzed reaction between o-hydroxyaryl azomethine ylides and MBH carbonates provides access to highly functionalized ?-aminobutyric acid derivatives in moderate to good yields. Mechanistically, the reaction involves a phosphine-catalyzed tandem SN2′/2-aza-Cope rearrangement/intramolecular addition process.

Ligand-Dependent Regiodivergent Enantioselective Allylic Alkylations of α-Trifluoromethylated Ketones

The asymmetric introduction of the CF3 unit is a powerful tool for modifying pharmacokinetic properties and slowing metabolic degradation in medicinal chemistry. A catalytic and enantioselective addition of α-CF3 enolates allows for expeditious access to

Synthesis of β-Lactams via Enantioselective Allylation of Anilines with Morita-Baylis-Hillman Carbonates

Enantioenriched β-lactams are accessed via enantioselective allylation of anilines with Morita-Baylis-Hillman carbonates followed by a base-promoted cyclization. The resulting 3-methyleneazetidin-2-ones are amenable to diastereoselective functionalization