113595-97-4

Basic information

• Product Name: Propanedioic acid, [[[3-(acetylamino)-4-fluorophenyl]amino]methylene]-, diethyl ester
• CAS NO: 113595-97-4
• Molecular Formula: C16H19FN2O5
• Molecular Weight: 338.336
• Mol File: 113595-97-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Propanedioic acid, [[[3-(acetylamino)-4-fluorophenyl]amino]methylene]-, diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Propanedioic acid, [[[3-(acetylamino)-4-fluorophenyl]amino]methylene]-, diethyl ester(113595-97-4)
• EPA Substance Registry System: Propanedioic acid, [[[3-(acetylamino)-4-fluorophenyl]amino]methylene]-, diethyl ester(113595-97-4)

Safety Data

• Hazardous Substances Data: 113595-97-4(Hazardous Substances Data)

Upstream product

• 454-07-9 N-(2-fluoro-5-nitrophenyl)acetamide 
• 75001-47-7 N-(5-amino-2-fluorophenyl)acetamide 
• 87-13-8 diethyl 2-ethoxymethylenemalonate 

Downstream Products

• 91524-15-1 Irloxacin 

Relevant articles and documents

1,7-phenanthrolines and their use as antifungal agents

There are disclosed compounds having the formula STR1 wherein R is hydrogen or lower alkyl; R1 is hydrogen, lower alkyl, lower alkenyl, lower alkynyl, phenyl or any of the foregoing substituted with halo; R2 is hydrogen, carboxy or l

Structure-Activity Relationships of Antibacterial 6,7- and 7,8-Disubstituted 1-Alkyl-1,4-dihydro-4-oxoquinoline-3-carboxylic Acids

Previous quantitative and qualitative structure-activity studies in antibacterial monosubstituted 1-ethyl-1,4-dihydro-4-oxoquinoline-3-carboxylic acids prompted us to synthesize the 6,7,8-polysubstituted compounds.In this paper, the preparation and antibacterial activity of the 6,7- and 7,8-disubstituted compounds and their derivatives are described.Among these compounds, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)quinoline-3-carboxylic acid (34) possessed many significant activities and was more active than oxolinic acid (84) against Gram-positive andGram-negative bacteria.Structure activity relationships are discussed.