113848-07-0

Basic information

• Product Name: Phosphonic acid, (2-oxo-4-phenyl-3-butenyl)-, diethyl ester, (E)-
• CAS NO: 113848-07-0
• Molecular Formula: C14H19O4P
• Molecular Weight: 282.276
• Mol File: 113848-07-0.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Phosphonic acid, (2-oxo-4-phenyl-3-butenyl)-, diethyl ester, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphonic acid, (2-oxo-4-phenyl-3-butenyl)-, diethyl ester, (E)-(113848-07-0)
• EPA Substance Registry System: Phosphonic acid, (2-oxo-4-phenyl-3-butenyl)-, diethyl ester, (E)-(113848-07-0)

Safety Data

• Hazardous Substances Data: 113848-07-0(Hazardous Substances Data)

Upstream product

• 3095-95-2 diethylphosphonoacetic acid 
• 22422-16-8 (E)-1-bromo-4-phenylbut-3-en-2-one 
• 762-04-9 phosphonic acid diethyl ester 
• 107487-00-3 (5-Phenyl-4,5-dihydro-isoxazol-3-ylmethyl)-phosphonic acid diethyl ester 
• 110841-50-4 N-<2-(diethoxyphosphoryl)ethylidene>hydroxylamine 
• 1606-75-3 (2-oxoethyl)phosphonic acid diethyl ester 
• 100-42-5 styrene 
• 100-52-7 benzaldehyde 
• 1067-71-6 Diethyl (2-oxopropyl)phosphonate 
• 867-13-0 diethoxyphosphoryl-acetic acid ethyl ester 
• 683-08-9 Diethyl methylphosphonate 
• 66130-90-3 diethyl <<(trimethylsilyl)oxy>carbonyl>methanephosphonate 
• 102-92-1 Cinnamoyl chloride 
• 113847-99-7 (4-Hydroxy-2-oxo-4-phenyl-butyl)-phosphonic acid diethyl ester 

Downstream Products

• 144890-18-6 (2,6-Dioxo-4,6-diphenyl-hexyl)-phosphonic acid diethyl ester 
• 144890-17-5 (2,6-Dioxo-4-phenyl-heptyl)-phosphonic acid diethyl ester 
• 1587708-63-1 (E)-diethyl (4-phenylbut-3-en-1-yn-1-yl)phosphonate 
• 1453071-57-2 (E)-4-phenyl-1-(tetrahydrofuran-2-yl)but-3-en-2-one 
• 5337-88-2 3-methyl-5-phenyl-2-cyclohexen-1-one 
• 144890-28-8 diethyl 2-methyl-4-phenyl-6-oxo-1-cyclohexenylphosphonate 
• 144890-29-9 5-phenylbicyclo<4.3.0>non-1-en-3-one 
• 120759-94-6 4-phenyl-4,4a,5,6,7,8-hexahydro-2(3H)-naphthalenone 
• 21154-23-4 3-(t-butyl)-5-phenyl-2-cyclohexen-1-one 
• 10346-08-4 3,5-diphenylcyclohex-2-en-1-one 
• 35225-79-7 dibenzylideneacetone 
• 115587-57-0 (dibenzylidene)acetone 

Relevant articles and documents

Base-induced one-pot preparation of N- or P-substituted alkynes

An efficient method for the formation of C(sp)-N or C(sp)-P bonds is described. The facile transformation proceeds under mild conditions (0 or -20 °C) in a one-pot manner, and does not require transition-metal catalysts. The base-induced protocol exhibits good functional group tolerance (up to 44 examples) and high efficiency (up to 94 % yield) towards rare heteroatom-substituted acetylenes (N or P). Furthermore, the proposed mechanism was supported by the isolation of a key intermediate. An efficient method for the formation of C(sp)-N or C(sp)-P bonds is described. The facile transformation proceeds in the absence of any transition-metal catalysts under mild conditions (0 or -20 °C) in a one-pot manner with good functional group compatibility and with high efficiency.

A practical synthesis of β-keto phosphonates from triethyl phosphonoacetate

An efficient and practical preparation of β-keto phosphonates, via acylation reaction of triethyl phosphonoacetate with carboxylic acid chlorides in the presence of magnesium chloride-triethylamine followed by decarbethoxylation, is described.

Synthesis of (Diethoxyphosphoryl)acetonitrile Oxide and Its Cycloaddition to Olefins. Synthetic Applications to 3,5-Disubstituted 2-Isoxazolines

(Diethoxyphosphoryl)acetonitrile oxide undergoes regioselective cycloaddition to olefins leading to 3--2-isoxazolines or -isoxazole.The phosphorus-stabilized carbanions generated by deprotonation of the cycloadducts can be util