114617-87-7

Basic information

• Product Name: Acetic acid, [4-[(diethylamino)sulfonyl]phenoxy]-, methyl ester
• CAS NO: 114617-87-7
• Molecular Formula: C13H19NO5S
• Molecular Weight: 301.364
• Mol File: 114617-87-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Acetic acid, [4-[(diethylamino)sulfonyl]phenoxy]-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid, [4-[(diethylamino)sulfonyl]phenoxy]-, methyl ester(114617-87-7)
• EPA Substance Registry System: Acetic acid, [4-[(diethylamino)sulfonyl]phenoxy]-, methyl ester(114617-87-7)

Safety Data

• Hazardous Substances Data: 114617-87-7(Hazardous Substances Data)

Upstream product

• 825-90-1 sodium p-hydroxybenzenesulfonate 
• 56077-78-2 4-(methyloxycarbonylmethylenoxy)benzenesulfonyl chloride 
• 109-89-7 diethylamine 
• 2065-23-8 methyl 2-phenoxyacetate 

Downstream Products

• 50283-86-8 (4-diethylsulfamoyl-phenoxy)-acetic acid 
• 91637-10-4 N,N-diethyl-4-(2-hydrazinyl-2-oxoethoxy)benzenesulfonamide 

Relevant articles and documents

Synthesis and insecticidal activity in vitro and vivo of novel benzenesulfonyl derivatives based on potent target subunit H of V-ATPase

Two lead compounds with benzenesulfonamide were found through virtual screening based on the 3D structure of the subunit H of V-ATPase in previous study. 74 benzenesulfonyl derivatives were synthesized and their insecticidal activities were evaluated. The derivatives with propargyl substituents exhibit excellent insecticidal activities against Mythimna separata Walker. The LD50 values of compounds A5.7 (28.0 μg·g?1) and B5.7 (36.4 μg·g?1) were significantly less than that of Celangulin V (344.0 μg·g?1). Furthermore, Isothermal Titration Calorimetry (ITC) data indicate there is a strong binding affinity between A5.7 and V-ATPase Subunit H. These results demonstrate that it is a practical way to develop pesticides targeting at H subunit of V-ATPase.