114790-35-1Relevant articles and documents
NEUROSTEROID COMPOUNDS AND METHODS FOR THEIR PREPARATION AND USE IN TREATING CENTRAL NERVOUS SYSTEM DISORDERS
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Paragraph 0103; 0125, (2019/11/12)
Described herein is the chemical structure of neurosteroid derivative compounds, methods of synthesizing the derivatives, and their uses in treating disorders, including those of the central nervous system. These compounds are readily synthesized and have improved pharmaceutical properties, including water solubility, compared to known neurosteroids.
Synthesis and in vitro evaluation of aspartate transcarbamoylase inhibitors
Coudray, Laetitia,Pennebaker, Anne F.,Montchamp, Jean-Luc
supporting information; experimental part, p. 7680 - 7689 (2010/03/24)
The design, synthesis, and evaluation of a series of novel inhibitors of aspartate transcarbamoylase (ATCase) are reported. Several submicromolar phosphorus-containing inhibitors are described, but all-carboxylate compounds are inactive. Compounds were sy
Prodrugs of compounds that inhibit TRPV1 receptor
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Page/Page column 21, (2010/11/27)
Compounds of formula (I) wherein A, R1, R2, and R3 are defined in the specification, and which are useful as therapeutic compounds particularly for treating disorders or conditions associated with inflammation, pain, bladd