115-69-5 Usage
Description
2-Amino-2-methyl-1,3-propanediol, also known as AMPD, is an aminodiol that is a propane-1,3-diol substituted by an amino and a methyl group at position 2. It is a white powder with various applications across different industries due to its unique chemical properties.
Uses
Used in Cosmetics Industry:
2-Amino-2-methyl-1,3-propanediol is used as an emulsifying agent for cosmetics, mineral oil, leather dressings, textile specialties, and cleaning compounds. It helps in blending immiscible substances, such as oil and water, to create stable mixtures.
Used in Soap Industry:
In the soap industry, 2-Amino-2-methyl-1,3-propanediol is used as an emulsifying agent for oils, fats, and waxes, contributing to the formation of stable emulsions and improving the texture and performance of soap products.
Used in Organic Synthesis:
2-Amino-2-methyl-1,3-propanediol is utilized in organic synthesis as a versatile building block for the creation of various chemical compounds, including surfactants and vulcanization accelerators.
Used as a Biological Buffer:
2-Amino-2-methyl-1,3-propanediol serves as a useful biological buffer, maintaining a stable pH environment in biological systems. It is particularly useful for enzymes with activity in the basic pH range, such as alkaline phosphatase.
Used in Hair Sprays:
In the hair care industry, 2-Amino-2-methyl-1,3-propanediol is used in hair sprays to provide hold and style retention while also offering conditioning benefits to the hair.
Used as an Absorbent for Acidic Gases:
2-Amino-2-methyl-1,3-propanediol acts as an absorbent for acidic gases, making it a valuable component in various industrial applications where gas absorption is required.
Used in the Preparation of 4-Hydroxymethyl-4-Methyl-Oxazolidin-2-One:
2-Amino-2-methyl-1,3-propanediol is also used in the preparation of 4-hydroxymethyl-4-methyl-oxazolidin-2-one, a compound with potential applications in various industries.
Used in the Determination of Alkaline Phosphatase Activity:
As a buffer, 2-Amino-2-methyl-1,3-propanediol is used in the determination of alkaline phosphatase activity, playing a crucial role in biochemical assays and research.
Used as a Spacer in Isotachophoresis of Proteins:
In the field of protein analysis, 2-Amino-2-methyl-1,3-propanediol serves as a spacer in isotachophoresis, a technique used to separate proteins based on their charge and size.
Purification Methods
Crystallise the diol three times from MeOH, dry in a stream of dry N2 at room temperature, then in a vacuum oven at 55o. Store it over CaCl2 [Hetzer & Bates J Phys Chem 66 308 1962]. [Beilstein 4 IV 1881.]
Check Digit Verification of cas no
The CAS Registry Mumber 115-69-5 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,1 and 5 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 115-69:
(5*1)+(4*1)+(3*5)+(2*6)+(1*9)=45
45 % 10 = 5
So 115-69-5 is a valid CAS Registry Number.
InChI:InChI=1/C4H11NO2/c1-4(5,2-6)3-7/h6-7H,2-3,5H2,1H3/p+1
115-69-5Relevant articles and documents
PROCESS FOR THE PREPARATION OF NITROALCOHOLS
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Paragraph 0020; 0021; 0025, (2013/09/26)
A process of preparing a nitroalcohol, e.g., 2-nitro-2-methyl-1-propane, from a nitropolyol, e.g., 2-nitro-2 -methyl-1,3-propanediol, the process comprising the step of contacting under hydrogenation conditions the nitropolyol with hydrogen, a hydrogenation catalyst and, optionally, a chelating agent.
A systematic entropy relationship for the general-base catalysis of the deprotonation of a carbon acid. A quantitative probe of transition-state solvation
Bunting, John W.,Stefanidis, Dimitrios
, p. 779 - 786 (2007/10/02)
The general-base-catalyzed deprotonation of a carbon acid, the l-methyl-4-(phenylacetyl)pyridinium cation (pKa = 9.02 at 25 °C), has been investigated for 32 general-base catalysts (25 amines and seven phenoxide ions) in aqueous solution. Amines give a generally scattered Bronsted plot; ring-substituted benzylamines have ?= 0.52, and ring-substituted phenoxides have ?= 0.60, with the phenoxides being more reactive than amines of similar basicity. The temperature dependences of the general-base-catalyzed deprotonation of this carbon acid have been measured over the range 15-45 °C for 12 base catalysts (eight primary, secondary, and tertiary amines; 4-(dimethylamino)pyridine; two phenoxide ions; hydroxide ion). The entropies of activation for these deprotonations show a clean curvilinear dependence upon the entropies of protonation of these base species, with the hydroxide ion being the only significant deviant from this relationship. This observation quantitatively establishes the importance of solvation effects as the major source of deviations that are commonly observed in Bronsted relationships for general-base-catalyzed processes.
Substituted pyridines
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, (2008/06/13)
This invention relates to substituted pyridines prepared by reacting aldehydes, amines, lower carboxylic acids such as acetic acid in the presence of oxygen. The N-substituted pyridinium salts formed can be converted to pyridines by thermal dealkylation. The reactions can be summarized by the following equations: STR1