1152427-93-4 Usage
Description
Trans-2-Phenylvinylboronic acid MIDA ester is a stable boronic acid derivative that is widely utilized in various chemical reactions and processes. It is characterized by its unique chemical structure and reactivity, making it a valuable compound in the field of organic chemistry.
Uses
Used in Chemical Synthesis:
Trans-2-Phenylvinylboronic acid MIDA ester is used as a reactant in Suzuki-Miyaura cross-coupling reactions, which are widely employed in the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and advanced materials. Its stability and reactivity make it a preferred choice for these types of reactions.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, trans-2-Phenylvinylboronic acid MIDA ester is used as a precursor to prepare α-borylated phenyl ketone via the Wacker-type oxidation method. trans-2-Phenylvinylboronic acid MIDA ester serves as a key intermediate in the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents.
Used in Material Science:
Trans-2-Phenylvinylboronic acid MIDA ester is also utilized in the field of material science, where it is employed in the synthesis of advanced materials with unique properties. Its ability to participate in various chemical reactions allows for the creation of novel materials with potential applications in electronics, energy storage, and other high-tech industries.
Check Digit Verification of cas no
The CAS Registry Mumber 1152427-93-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,5,2,4,2 and 7 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1152427-93:
(9*1)+(8*1)+(7*5)+(6*2)+(5*4)+(4*2)+(3*7)+(2*9)+(1*3)=134
134 % 10 = 4
So 1152427-93-4 is a valid CAS Registry Number.
1152427-93-4Relevant articles and documents
Synthesis of α-Borylated Ketones by Regioselective Wacker Oxidation of Alkenylboronates
Corless, Victoria B.,Holownia, Aleksandra,Foy, Hayden,Mendoza-Sanchez, Rodrigo,Adachi, Shinya,Dudding, Travis,Yudin, Andrei K.
supporting information, p. 5300 - 5303 (2018/09/12)
As part of a program aimed at metal-catalyzed oxidative transformations of molecules with carbon-metalloid bonds, the synthesis of α-borylated ketones is reported via regioselective TBHP-mediated Wacker-type oxidation of N-methyliminodiacetic acid (MIDA)-protected alkenylboronates. The observed regioselectivity correlates with the hemilabile nature of the B-N dative bond in the MIDA boronate functional group, which allows boron to guide selectivity through a neighboring group effect.
Access to Cyclic Amino Boronates via Rhodium-Catalyzed Functionalization of Alkyl MIDA Boronates
St. Denis, Jeffrey D.,Lee, C. Frank,Yudin, Andrei K.
, p. 5764 - 5767 (2015/12/11)
Herein, we describe the rhodium-catalyzed C-H amination reaction of 1,2-boryl sulfamate esters derived from amphoteric α-boryl aldehydes. Depending on the substitution pattern of the boryl sulfamate ester, a diverse range of five- or six-membered ring heterocycles are accessible using this transformation. The highly chemoselective nature of the C-H functionalization reaction preserves the alkyl boronate functional group, which enables the synthesis of B-C-N and B-C-C-N motifs that are present in a number of hydrolase inhibitors.
