115290-80-7

Basic information

• Product Name: (3S) 3-phenyl-3-(2-methylphenoxy)propyl methanesulfonate
• Synonyms: (3S) 3-phenyl-3-(2-methylphenoxy)propyl methanesulfonate
• CAS NO: 115290-80-7
• Molecular Weight: 320.409
• Mol File: 115290-80-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (3S) 3-phenyl-3-(2-methylphenoxy)propyl methanesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: (3S) 3-phenyl-3-(2-methylphenoxy)propyl methanesulfonate(115290-80-7)
• EPA Substance Registry System: (3S) 3-phenyl-3-(2-methylphenoxy)propyl methanesulfonate(115290-80-7)

Safety Data

• Hazardous Substances Data: 115290-80-7(Hazardous Substances Data)

Upstream product

• 104196-23-8 (2S,3S)-2,3-epoxy-3-phenyl-1-propanol 
• 100-52-7 benzaldehyde 
• 103548-16-9 (R)-3-phenyl-1,3-dihydroxypropane 
• 72656-47-4 ethyl (R)-3-hydroxy-3-phenylpropanoate 
• 5764-85-2 Ethyl 3-hydroxy-3-phenylpropanoate 
• 118856-08-9 butyric acid 2-ethoxycarbonyl-1-phenyl-ethyl ester 
• 95-48-7 ortho-cresol 
• 115290-78-3 (1R) 3-phenyl-3-hydroxypropyl methanesulfonate 

Downstream Products

• 82857-39-4 -(+)-tomoxetine hydrochloride 
• 105314-53-2 (S)-N-methyl-3-(2-methylphenoxy)-3-phenyl-1-propanamine 

Relevant articles and documents

Asymmetric Synthesis of Both Enantiomers of Tomoxetine and Fluoxetine. Selective Reduction of 2,3-Epoxycinnamyl Alcohol with Red-Al.

Both enantiomers of tomoxetine 7a,7b and fluoxetine 8a,8b (as their hydrochloride salts) have been synthetized from cinnamyl alkohol by asymmetric epoxidation, and their absolute configurations have been established.Optimal conditions for regioselective Red-Al reduction at C-2 of 2,3-epoxycinnamyl alcohol are discussed.