115406-35-4

Basic information

• Product Name: 3-((S)-1-Hexadecyloxymethyl-2-trityloxy-ethoxy)-isoxazole
• CAS NO: 115406-35-4
• Molecular Weight: 625.892
• Mol File: 115406-35-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-((S)-1-Hexadecyloxymethyl-2-trityloxy-ethoxy)-isoxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-((S)-1-Hexadecyloxymethyl-2-trityloxy-ethoxy)-isoxazole(115406-35-4)
• EPA Substance Registry System: 3-((S)-1-Hexadecyloxymethyl-2-trityloxy-ethoxy)-isoxazole(115406-35-4)

Safety Data

• Hazardous Substances Data: 115406-35-4(Hazardous Substances Data)

Upstream product

• 92471-46-0 (R)-3-(1-hexadecyloxy)-1-(trityloxy)propan-2-ol 
• 5777-20-8 isoxazol-3-ol 
• 115406-33-2 1-O-hexadecyl-2-O-(3-isoxazolyl)-3-O-triphenylmethyl-sn-glycerol 

Relevant articles and documents

An efficient synthesis of Platelet-Activating Factor (PAF) via 1-o-alkyl-2-o-(3-isoxazolyl)-SN-glycero-3-phosphocholine, a new PAF agonist utilization of the 3-isoxazolyloxy group as a protected hydroxyl

Potent PAF agonists (R)-3a,b were synthesized and converted into PAF. Key steps include Mitsunobu reaction of a chiral secondary alcohol with 3-hydroxyisoxazole as the acidic component, and hydrogenolytic ring cleavage of the resulting 3-isoxazolyloxy gro