92471-46-0Relevant articles and documents
Platelet activating factor derivative and synthesis method thereof
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Paragraph 0035; 0043; 0044, (2017/08/29)
The invention belongs to the technical field of chemical synthesis and discloses a platelet activating factor derivative with a formula (I) structure, wherein a substituent group R refers to an acryl group. A synthetic route includes nine-step reaction by taking chiral source S-configuration solketal as a starting reactant. The method is adopted for synthesis of a 2-sulfo platelet activating factor and a derivative thereof for the first time and has advantages of high yield, easiness in separation and the like. Low-cost batch synthesis of 2-S-PAF and the derivative thereof is realized, and significances to activity research of 2-S-PAF and the derivative thereof, biological experiments, clinical application and disease treatment are achieved.
Structure and synthesis of a unique isonitrile lipid isolated from the marine mollusk actinocyclus papillatus
Manzo, Emiliano,Carbone, Marianna,Mollo, Ernesto,Irace, Carlo,Di Pascale, Antonio,Li, Yan,Ciavatta, Maria Letizia,Cimino, Guido,Guo, Yue-Wei,Gavagnin, Margherita
supporting information; experimental part, p. 1897 - 1899 (2011/06/21)
The first chemical study of an Actinocyclidae nudibranch, Actinocyclus papillatus, resulted in the isolation of (-)-actisonitrile (1), a lipid based on a 1,3-propanediol ether skeleton. The structure was established by spectroscopic methods, whereas the a
OXIDIZED LIPID COMPOUNDS AND USES THEREOF
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Page/Page column 57, (2010/06/11)
Novel oxidized lipids are provided herein, as well as methods for producing same, and uses thereof in treating or preventing an inflammation associated with endogenous oxidized lipids and related conditions.