1154520-35-0

Basic information

• Product Name: 3-(4-acetyl-phenyl)-2-[4-amino-2-(4-chlorophenylamino)-thiazol-5-yl]-3H-quinazolin-4-one
• CAS NO: 1154520-35-0
• Molecular Weight: 487.969
• Mol File: 1154520-35-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(4-acetyl-phenyl)-2-[4-amino-2-(4-chlorophenylamino)-thiazol-5-yl]-3H-quinazolin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-acetyl-phenyl)-2-[4-amino-2-(4-chlorophenylamino)-thiazol-5-yl]-3H-quinazolin-4-one(1154520-35-0)
• EPA Substance Registry System: 3-(4-acetyl-phenyl)-2-[4-amino-2-(4-chlorophenylamino)-thiazol-5-yl]-3H-quinazolin-4-one(1154520-35-0)

Safety Data

• Hazardous Substances Data: 1154520-35-0(Hazardous Substances Data)

Upstream product

• 748165-98-2 2-chloromethyl-3-(p-acetylphenyl)-3H-quinazolin-4-one 
• 7464-17-7 1-amidino-3-(4-chlorophenyl)thiourea 

Relevant articles and documents

Design, synthesis and characterization of novel 2-(2,4-disubstituted-thiazole-5-yl)-3-aryl-3H-quinazoline-4-one derivatives as inhibitors of NF-κB and AP-1 mediated transcription activation and as potential anti-inflammatory agents

A series of 2-(2,4-disubstituted-thiazole-5-yl)-3-aryl-3H-quinazoline-4-one derivatives were designed and synthesized. Synthesized molecules were further evaluated for their inhibitory activity towards transcription factors NF-κB and AP-1 mediated transcr