115545-70-5

Basic information

• Product Name: Boc-Glu(OBzl)-Asp(O-2-Ada)-Gly-OBzl
• CAS NO: 115545-70-5
• Molecular Weight: 733.859
• Mol File: 115545-70-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Boc-Glu(OBzl)-Asp(O-2-Ada)-Gly-OBzl(CAS DataBase Reference)
• NIST Chemistry Reference: Boc-Glu(OBzl)-Asp(O-2-Ada)-Gly-OBzl(115545-70-5)
• EPA Substance Registry System: Boc-Glu(OBzl)-Asp(O-2-Ada)-Gly-OBzl(115545-70-5)

Safety Data

• Hazardous Substances Data: 115545-70-5(Hazardous Substances Data)

Upstream product

• 115545-73-8 Boc-Asp-(O-2-Ada)-OSu 
• 118534-84-2 Boc-Asp(O-2-Ada)-Gly-OBzl 
• 118534-76-2 Boc-Asp(O-2-Ada)-OBzl 
• 115545-58-9 Boc-Asp(O-2-Ada)-OH 
• 700-57-2 1-adamantanol 
• 7536-59-6 Boc-Glu(OBzl)-ONp 
• 115545-69-2 H-Asp(O-2-Ada)-Gly-OBzl 

Downstream Products

• 115545-72-7 Z-Glp-Glu(OBzl)-Asp(O-2-Ada)-Gly-OBzl 
• 91856-42-7 H-Glp-Glu-Asp-Gly-OH 

Relevant articles and documents

Amino Acids and Peptides. Part 19. Synthesis of β-1-and β-2-Adamantyl Aspartates and their Evaluation for Peptide Synthesis

β-1-and β-2-Adamantyl aspartates have been synthesized and their properties examined.Altough the 1-Ada group is labile to TFA, the 2-Ada group is unaffected during TFA treatment, but easily removable by methanesulphonic acid (MSA) at room temperature within 5 min.Both groups are unaffected by treatment with 55percent piperidine under conditions which easily cleave the fluoren-9-ylmethoxycarbonyl (Fmoc) group from α-amino group.Both groups can suppress aspartimide formation as a side reaction under acidic and basic conditions during the synthesis of aspartyl peptides. β-1-or β-2-Adamantyl aspartates may be applicable to solid-phase peptide synthesis in combination with Fmoc or Boc as an Nα-protecting group, respectively.Some properties of the aspartimide moiety are described.