115665-78-6

Basic information

• Product Name: trans-1-(2-bromovinyl)-4-(trifluoromethyl)benzene
• Synonyms: trans-1-(2-bromovinyl)-4-(trifluoromethyl)benzene
• CAS NO: 115665-78-6
• Molecular Weight: 251.046
• Mol File: 115665-78-6.mol
• Article Data: 23

Chemical Properties

• CAS DataBase Reference: trans-1-(2-bromovinyl)-4-(trifluoromethyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: trans-1-(2-bromovinyl)-4-(trifluoromethyl)benzene(115665-78-6)
• EPA Substance Registry System: trans-1-(2-bromovinyl)-4-(trifluoromethyl)benzene(115665-78-6)

Safety Data

• Hazardous Substances Data: 115665-78-6(Hazardous Substances Data)

Upstream product

• 455-13-0 4-Iodobenzotrifluoride 
• 14275-61-7 (E)-1,2-bis(tri-n-butylstannyl)ethene 
• 402-43-7 p-trifluoromethylphenyl bromide 
• 75-25-2 Bromoform 
• 189096-91-1 {[4-(trifluoromethyl)phenyl]methylidene}hydrazine 
• 2062-26-2 3-<4'-(trifluoromethyl)phenyl>-2-propenoic acid 
• 131356-53-1 1-(2,2-dibromovinyl)-4-(trifluoromethyl)benzeney 
• 1206604-45-6 (E)-2-(4-trifluoromethyl)phenyleth-1-enyldicyclohexylborane 
• 402-49-3 4-bromomethyltrifluoromethylbenzene 
• 74-95-3 1,1-dibromomethane 
• 952739-61-6 (E)-1-(2-iodovinyl)-4-(trifluoromethyl)-benzene 
• 455-19-6 4-Trifluoromethylbenzaldehyde 
• 1059140-27-0 1-(2-bromovinyl)-4-(trifluoromethyl)benzene 
• 705-31-7 4-trifluoromethylphenylacetylene 

Downstream Products

• 1344717-55-0 (E)-9-benzyl-6-(benzylthio)-8-(4-(trifluoromethyl)styryl)-9H-purine 
• 139913-94-3 (E)-1-chloro-2-ethene 
• 1068616-21-6 (E)-(4-trifluoromethylstyryl)(phenyl)sulfane 
• 1097939-29-1 1-((E)-4,5-dimethylhexa-1,4-dienyl)-4-(trifluoromethyl)benzene 
• 1027335-55-2 (E)-2-(4-(trifluoromethyl)styryl)pyridine 

Relevant articles and documents

Transfer of alk-1-enyl group from boron to tin: A highly stereoselective synthesis of (E)-alk-1-enyltributylstannanes

Treatment of (E)-alk-1-enyldicyclohexylboranes with tributyltin methoxide in the presence of galvinoxyl (1 mol%) at room temperature results in transfer of the alk-1-enyl group from boron to tin to give (E)-alk-1- enyltributylstannanes in a highly stereoselective fashion. Subsequent halodestannylation of (E)-alk-1-enyltributylstannanes is allowed to proceed in a one-pot manner to produce the corresponding (E)-1-iodoalk-1-enes and (E)-1-bromoalk-1-enes in good to high yields, respectively. Georg Thieme Verlag Stuttgart.

Selective Rhodium-Catalyzed Hydroformylation of Terminal Arylalkynes and Conjugated Enynes to (Poly)enals Enabled by a π-Acceptor Biphosphoramidite Ligand

The hydroformylation of terminal arylalkynes and enynes offers a straightforward synthetic route to the valuable (poly)enals. However, the hydroformylation of terminal alkynes has remained a long-standing challenge. Herein, an efficient and selective Rh-catalyzed hydroformylation of terminal arylalkynes and conjugated enynes has been achieved by using a new stable biphosphoramidite ligand with strong π-acceptor capacity, which affords various important E-(poly)enals in good yields with excellent chemo- and regioselectivity at low temperatures and low syngas pressures.

Illuminatinganti-hydrozirconation: controlled geometric isomerization of an organometallic species

A general strategy to enable the formalanti-hydrozirconation of arylacetylenes is reported that mergescis-hydrometallation using the Schwartz Reagent (Cp2ZrHCl) with a subsequent light-mediated geometric isomerization atλ= 400 nm. Mechanistic delineation of thecontra-thermodynamic isomerization step indicates that a minor reaction product functions as an efficientin situgenerated photocatalyst. Coupling of theE-vinyl zirconium species with an alkyne unit generates a conjugated diene: this has been leveraged as a selective energy transfer catalyst to enableE→Zisomerization of an organometallic species. Through anUmpolungmetal-halogen exchange process (Cl, Br, I), synthetically useful vinyl halides can be generated (up toZ?:?E= 90?:?10). This enabling platform provides a strategy to access nucleophilic and electrophilic alkene fragments in both geometric forms from simple arylacetylenes.