116028-05-8

Basic information

• Product Name: 3,3,4-triphenyl-1-(p-tolyl)azetidin-2-one
• Synonyms: 3,3,4-triphenyl-1-(p-tolyl)azetidin-2-one
• CAS NO: 116028-05-8
• Molecular Weight: 389.497
• Mol File: 116028-05-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3,3,4-triphenyl-1-(p-tolyl)azetidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3,3,4-triphenyl-1-(p-tolyl)azetidin-2-one(116028-05-8)
• EPA Substance Registry System: 3,3,4-triphenyl-1-(p-tolyl)azetidin-2-one(116028-05-8)

Safety Data

• Hazardous Substances Data: 116028-05-8(Hazardous Substances Data)

Upstream product

• 1613-92-9 (E)-N-benzylidene-4-toluidine 
• 525-06-4 diphenyl ketene 
• 134-81-6 benzil 
• 2272-45-9 benzal-p-toluidine 

Relevant articles and documents

Photoredox Catalytic Phosphite-Mediated Deoxygenation of α-Diketones Enables Wolff Rearrangement and Staudinger Synthesis of β-Lactams

A novel visible-light-driven catalytic activation of C=O bonds by exploiting the photoredox chemistry of 1,3,2-dioxaphospholes, readily accessible from α-diketones and trialkyl phosphites, is reported. This mild and environmentally friendly strategy provides an unprecedented and efficient access to the Wolff rearrangement reaction which traditionally entails α-diazoketones as precursors. The resulting ketenes could be precisely trapped by alcohols/thiols to give α-aryl (thio)acetates and by imines to afford the valuable β-lactams in up to 99 % yields.