116118-03-7

Basic information

• Product Name: Benzene, 1,1'-[(1E)-3-methoxy-1-propene-1,3-diyl]bis-
• CAS NO: 116118-03-7
• Molecular Formula: C16H16O
• Molecular Weight: 224.302
• Mol File: 116118-03-7.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: Benzene, 1,1'-[(1E)-3-methoxy-1-propene-1,3-diyl]bis-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1,1'-[(1E)-3-methoxy-1-propene-1,3-diyl]bis-(116118-03-7)
• EPA Substance Registry System: Benzene, 1,1'-[(1E)-3-methoxy-1-propene-1,3-diyl]bis-(116118-03-7)

Safety Data

• Hazardous Substances Data: 116118-03-7(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 87751-69-7 rac-(E)-1,3-diphenyl-3-acetoxy-prop-1-ene 
• 3412-44-0 1,3-diphenylpropene 
• 26958-41-8 cinnamyl-1,3-dithiane 
• 591-51-5 phenyllithium 
• 104-55-2 3-phenyl-propenal 
• 536-74-3 phenylacetylene 
• 100-52-7 benzaldehyde 
• 53395-25-8 1,1'-(3-methoxyprop-1-yne-1,3-diyl)dibenzene 
• 116117-95-4 1,3-diphenyl-1-methoxy-2-phenylselenenyl propane 
• 3412-44-0 (1E)-1,3-diphenylpropene 
• 614-47-1 1,3-diphenyl-propen-3-one 
• 4364-06-1 (E)-cinnamaldehyde dimethylacetal 
• 62668-02-4 (E)-1,3-diphenyl-2-propen-1-ol 

Downstream Products

• 106137-98-8 (R)-(E)-1,3-diphenyl-3-trimethylsilylpropene 
• 54848-77-0 C₁₆H₁₆O 
• 26278-69-3 1,3-diphenyl-1,3-dimethoxy propane 
• 34293-21-5 rac-(1E, 5E)-1,3,4,6-tetraphenyl-1,5-hexadiene 
• 71117-29-8 meso-(1E, 5E)-1,3,4,6-tetraphenyl-1,5-hexadiene 
• 3412-44-0 (1E)-1,3-diphenylpropene 
• 91-47-4 2,3-diphenylacrylic acid 
• 116118-10-6 1,3-diphenyl-1,3-dimethoxy-2-phenylselenenyl propane 

Relevant articles and documents

Cobalt-catalyzed allylic substitution reaction of allylic ethers with phenyl and trimethylsilylmethyl grignard reagents

Treatment of cinnamyl methyl ether with phenylmagnesium bromide in ether in the presence of CoCl2[1,5-bis(diphenylphosphino)pentane] affords 1,3-diphenylpropene in good yield. Similar allylic substitution reaction with trimethylsilylmethylmagne

Nickel-Mediated Enantiospecific Silylation via Benzylic C-OMe Bond Cleavage

Benzylic stereocenters are found in bioactive and drug molecules, as enantiopure benzylic alcohols have been used to build such a stereogenic center, but are limited to the construction of a C-C bond. Silylation of alkyl alcohols has the potential to build bioactive molecules and building blocks; however, the development of such a process is challenging and unknown. Herein, we describe an unprecedented AgF-assisted nickel catalysis in the enantiospecific silylation of benzylic ethers.

Water promoted allylic nucleophilic substitution reactions of (: E)-1,3 diphenylallyl acetate

A transition metal free, water based, greener protocol for the allylic alkylation, allylic amination, O-allylation of (E)-1,3-diphenylallyl acetate is described. The developed methodology is applicable for a wide range of nucleophiles furnishing excellent yields of corresponding products up to 87% under mild reaction conditions. A distinct effect of water and base is explored for allylic nucleophilic substitution reactions of (E)-1,3-diphenylallyl acetate.

TRACELESS DIRECTING GROUPS IN RADICAL CASCADES: FROM OLIGOALKYNES TO FUSED HELICENES WITHOUT TETHERED INITATORS

The present disclosure is directed to a traceless directing group in a radical cascade. The chemo- and regioselectivity of the initial attack in skipped oligoalkynes is controlled by a propargyl alkoxy moiety. Radical translocations lead to the boomerang return of radical center to the site of initial attack where it assists to the elimination of the directing functionality via β-scission in the last step of the cascade. In some aspects, the reaction of the present invention is catalyzed by a stannane moiety, which allows further via facile reactions with electrophiles as well as Stille and Suzuki cross-coupling reactions. This selective radical transformation opens a new approach for the controlled transformation of skipped oligoalkynes into polycyclic ribbons of tunable dimensions.