1163681-54-6

Basic information

• Product Name: N-[3-chloro-1-methylpyridin-2(1H)-ylidene]aniline
• Synonyms: N-[3-chloro-1-methylpyridin-2(1H)-ylidene]aniline
• CAS NO: 1163681-54-6
• Molecular Weight: 218.686
• Mol File: 1163681-54-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-[3-chloro-1-methylpyridin-2(1H)-ylidene]aniline(CAS DataBase Reference)
• NIST Chemistry Reference: N-[3-chloro-1-methylpyridin-2(1H)-ylidene]aniline(1163681-54-6)
• EPA Substance Registry System: N-[3-chloro-1-methylpyridin-2(1H)-ylidene]aniline(1163681-54-6)

Safety Data

• Hazardous Substances Data: 1163681-54-6(Hazardous Substances Data)

Upstream product

• 2402-77-9 2,3-dichloro-pyridine 
• 1422377-92-1 2,3-dichloro-1-methylpyridinium trifluoromethanesulfonate 
• 62-53-3 aniline 
• 6604-94-0 3-chloro-N-phenyl-2-aminopyridine 
• 74-88-4 methyl iodide 
• 1163681-53-5 3-chloro-2-iodo-1-methylpyridinium iodide 

Relevant articles and documents

base effect in the auto-tandem palladium-catalyzed synthesis of amino-substituted 1-methyl-1H-α-carbolines

An auto-tandem Pd-catalyzed process consisting of an intramolecular direct arylation and an intermolecular Buchwald-Hartwig reaction for C-ring amino-substituted 1-methyl-1H-α-carboline synthesis has been developed. A mechanistic study of the direct arylation reaction revealed a rate effect of the inorganic base on the C-H activation step ( base effect ). The amines, reagents in the tandem protocol, appear to have a similar effect on the direct arylation.