116400-82-9Relevant articles and documents
Synthesis of Benzo-Fused Benzodiazepines Employed as Probes of the Agonist Pharmacophore of Benzodiazepine Receptors
Zhang, Weijiang,Koehler, Konrad F.,Harris, Bradford,Skolnick, Phil,Cook, James M.
, p. 745 - 757 (2007/10/02)
The synthesis and in vitro evaluation of benzo-fused benzodiazepines 1-6 are described.These "molecular yardsticks" were employed to probe the spatial dimensions of the lipophilic pocket L2 in the benzodiazepine receptor (BzR) cleft and to dete