3837-42-1Relevant articles and documents
Metal-Free Synthesis of Benzo[a]phenanthridines from Aromatic Aldehydes, Cyclohexanones, and Aromatic Amines
Chen, Shanping,Deng, Guo-Jun,Jiang, Pingyu,Jiang, Shuxin,Shan, Zhifei,Wang, Quanyuan,Zheng, Haolin
supporting information, p. 365 - 370 (2021/12/27)
A three-component synthesis of benzo[α]phenanthridines from aromatic aldehydes, cyclohexanones, and aromatic amines has been developed, which is mediated by KI/DMSO/camphorsulfonic acid to afford a variety of functionalized benzo[α]phenanthridines in satisfactory yields. The present strategy provides a biaryl motif ortho to the nitrogen atom which has the potential to be used as ligand by further modification. With the advantages of readily available starting materials, transition-metal-free conditions, gram-scale synthesis, and broad substrate scope, this three-component protocol provides an efficient approach for the preparation of diverse benzo[α]phenanthridines.
Regioselective synthesis of benzo[g]- and benzo[f]quinolines by reaction of chalcones with naphthalen-2-amine
Pak,Bykov, Ya. V.,Yaganova,Gorbunov,Glushkov,Dmitriev,Slepukhin
, p. 562 - 568 (2017/06/06)
Reactions of 4- and 4′-substituted chalcones with naphthalen-2-amine afforded isomeric benzo[g]- and benzo[f]quinoline derivatives. Depending on the substituent in the initial chalcone, the cyclization follows two pathways through different intermediates.
Molecular iodine-catalyzed and air-mediated tandem synthesis of quinolines via three-component reaction of amines, aldehydes, and alkynes
Li, Xuejian,Mao, Zhenjun,Wang, Yanguang,Chen, Weixiang,Lin, Xufeng
experimental part, p. 3858 - 3862 (2011/06/21)
A one-pot synthesis of quinolines via molecular iodine-catalyzed and air-mediated tandem condensation/imino-Diels-Alder/isomerization/oxidation of simple readily available amines, aldehydes, and alkynes has been developed. This methodology was extended to synthesize quinazolines from two molecules of amines and two molecules of glyoxalates.
