116707-98-3

Basic information

• Product Name: N-(2-bromo-4-methoxyphenyl)-N-methylacrylamide
• Synonyms: N-(2-bromo-4-methoxyphenyl)-N-methylacrylamide
• CAS NO: 116707-98-3
• Molecular Weight: 270.126
• Mol File: 116707-98-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: N-(2-bromo-4-methoxyphenyl)-N-methylacrylamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-bromo-4-methoxyphenyl)-N-methylacrylamide(116707-98-3)
• EPA Substance Registry System: N-(2-bromo-4-methoxyphenyl)-N-methylacrylamide(116707-98-3)

Safety Data

• Hazardous Substances Data: 116707-98-3(Hazardous Substances Data)

Upstream product

• 116707-97-2 N-(2-bromo-4-methoxyphenyl)acrylamide 
• 74-88-4 methyl iodide 
• 591-20-8 3-Bromophenol 
• 98447-30-4 2-bromo-4-methoxy-1-nitrobenzene 
• 5470-65-5 3-bromo-4-nitrophenol 
• 32338-02-6 2-bromo-4-methoxyaniline 

Downstream Products

• 324520-87-8 3-[(2-bromo-4-methoxy-phenyl)-methyl-carbamoyl]-pyrrole-1-carboxylic acid tert-butyl ester 
• 324520-81-2 N-(2-bromo-4-methoxyphenyl)-N-methyl-1H-3-pyrrolecarboxamide 
• 116707-99-4 1,3-dimethyl-5-methoxyindolin-2-one 

Relevant articles and documents

Rh-Catalyzed Domino Addition-Enolate Arylation: Generation of 3-Substituted Oxindoles via a Rh(lll) Intermediate

A Rh-catalyzed domino conjugate addition-arylation sequence via a Rh(III) intermediate is reported. This process involving a proposed intramolecular oxidative addition of a rhodium enolate was utilized to achieve the synthesis of 3-substituted oxindole derivatives in moderate to excellent yields.

Indirect Electroreductive Cyclisation of N-Allylic and N-Propargylbromo Amides and o-Bromoacryloylanilides using Nickel(II) Complexes as Electron-transfer Catalysts

Nickel(II) complex-catalysed indirect electroreduction of N-allylic and N-propargyl-α-bromo amides and o-bromoacryloylanilides gave the corresponding 5-membered lactams.The product distribution was affected by the ability of the solvent to donate hydrogen atom.The electroreduction of N-allyl-N-(bromoacetyl)toluene-p-sulfonamide 1a in DMF and acetonitrile yielded as main product the 4-methylpyrrolidinone 2a (41percent) and the 4-(bromomethyl)pyrrolidinone 3a (33percent), respectively.On addition of 2 mol equiv. of a hydrogen-atom donor (Ph2PH) to the reaction of bromo amide 1a in acetonitrile, compound 1a provided compound 2a (58percent) as the sole cylised product.