117-08-8 Usage
Chemical Properties
white needle-like crystals or powder
Uses
Different sources of media describe the Uses of 117-08-8 differently. You can refer to the following data:
1. Intermediate in dyes, pharmaceuticals, plasticizers,
and other organic materials; flame-retardant
in epoxy resins.
2. Tetrachlorophthalic Anhydride is used in the synthesis of nucleoside analogues with a specific structure as apoptosis inducing active compounds. Also used in the synthesis of carbonic anhydrase inhbitors. Chlorinated Reactive Flame Retardant Intermediate
Definition
ChEBI: A cyclic dicarboxylic anhydride that is phthalic anhydride chlorinated at the 4-, 5-, 6- and 7-positions.
General Description
Odorless needle-like crystals or white powder.
Air & Water Reactions
Sensitive to air and moisture.
Reactivity Profile
4,5,6,7-Tetrachloro-1,3-isobenzofurandione reacts exothermically with water. This reaction is expected to be slow, but can become vigorous if local heating accelerates it. Reaction with water is accelerated by acids. Incompatible with acids, strong oxidizing agents, alcohols, amines, and bases.
Fire Hazard
Flash point data for 4,5,6,7-Tetrachloro-1,3-isobenzofurandione are not available. 4,5,6,7-Tetrachloro-1,3-isobenzofurandione is probably combustible.
Flammability and Explosibility
Notclassified
Purification Methods
Crystallise the anhydride from chloroform or *benzene, then sublime it in a vacuum. [Beilstein 17/11 V 260.]
Check Digit Verification of cas no
The CAS Registry Mumber 117-08-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,1 and 7 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 117-08:
(5*1)+(4*1)+(3*7)+(2*0)+(1*8)=38
38 % 10 = 8
So 117-08-8 is a valid CAS Registry Number.
InChI:InChI=1/C8Cl4O3/c9-3-1-2(8(14)15-7(1)13)4(10)6(12)5(3)11
117-08-8Relevant articles and documents
Rapid and convenient microwave-assisted synthesis of aromatic imides and N-hydroxymethylimides
Kacprzak, Karol
, p. 1499 - 1507 (2003)
Extremely simple high-yielding and rapid microwave-assisted synthesis of wide array of aromatic mono and diimides and mono- and bis-N-hydroxymethylimides is reported.
In vitro method to detect allergic reactions to low molecular weight chemicals
-
, (2008/06/13)
This invention relates to the use of IgE sensitized basophiles and mast cells in invitrotests to determine histamine release when challenged with small molecular weight chemical haptens conjugated to protein, e.g., human serum albumin.
Halogenated polyol-ester neutralization agent
-
, (2008/06/13)
Haze-free reactive flame retardant halo polyols are made by reacting (a) a halogen containing cyclic acid anhydride (e.g. tetrabromophthalic anhydride), (b) an aliphatic polyol, e.g. diethylene glycol, and (c) an epoxide, e.g. propylene oxide, and including potassium salt of fatty acids (e.g. potassium acetate) in the reaction mixture in an amount at least sufficient to neutralize residual sulfuric acid that is usually present in the halogen containing cyclic acid anhydride.