117194-63-5Relevant articles and documents
SYNTHESIS OF TWO LINEAR OCTAPEPTIDE FRAGMENTS OF CYCLOSPORIN BY STEPWISE AND FRAGMENT CONDENSATION STRATEGIES
Galpin, I. J.,Mohammed, A. K. A.,Patel, A.,Priestley, G.
, p. 1763 - 1772 (2007/10/02)
The octapeptide Z-(Me)Leu-Val-(Me)Leu-Ala-D-Ala-(Me)Leu-(Me)Leu-(Me)Val-O(t-Bu) was prepared by stepwise elongation starting from H-(Me)Val-O(t-Bu).Diphenylphosphinic mixed anhydrides were preferentially used throughout as they gave high yields of optical