89537-02-0

Basic information

• Product Name: L-Valine, N-methyl-N-[N-methyl-N-[(phenylmethoxy)carbonyl]-L-leucyl]-, 1,1-dimethylethyl ester
• CAS NO: 89537-02-0
• Molecular Formula: C25H40N2O5
• Molecular Weight: 448.603
• Mol File: 89537-02-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: L-Valine, N-methyl-N-[N-methyl-N-[(phenylmethoxy)carbonyl]-L-leucyl]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Valine, N-methyl-N-[N-methyl-N-[(phenylmethoxy)carbonyl]-L-leucyl]-, 1,1-dimethylethyl ester(89537-02-0)
• EPA Substance Registry System: L-Valine, N-methyl-N-[N-methyl-N-[(phenylmethoxy)carbonyl]-L-leucyl]-, 1,1-dimethylethyl ester(89537-02-0)

Safety Data

• Hazardous Substances Data: 89537-02-0(Hazardous Substances Data)

Upstream product

• 117194-65-7 Z-(Me)Leu-O-(t-Bu) 
• 103478-58-6 Fmoc-N-methylvaline 
• 23161-76-4 N-(Benzyloxycarbonyl)-N-methyl-(S)-valin-tert-butylester 
• 45170-31-8 Boc-N-Me-Val-OH 
• 42417-65-2 Z-MeVal-OH 
• 33099-08-0 N-benzyloxycarbonyl-N-methyl-L-leucine 
• 5616-87-5 N-Methyl-(S)-valin-tert-butylester 
• 103478-59-7 Fmoc-MeVal-O-t-Bu 
• 103478-72-4 Fmoc-(Me)Val-Cl 

Downstream Products

• 89537-04-2 N-(Benzyloxycarbonyl)-N-methyl-(S)-leucyl-N-methyl-(S)-leucyl-N-methyl-(S)-valin-tert-butylester 
• 117194-59-9 Z-Ala-D-Ala-(Me)Leu-(Me)Leu-(Me)Val-O-(t-Bu) 
• 117194-54-4 Z-(Me)Leu-Val-(Me)Leu-Ala-D-Ala-(Me)Leu-(Me)Leu-(Me)Val-O-(t-Bu) 
• 117194-63-5 Z-(Me)Leu-Ala-D-Ala-(Me)Leu-(Me)Leu-(Me)Val-O-(t-Bu) 
• 109745-92-8 N-(Benzyloxycarbonyl)-(R)-alanyl-N-Methyl-(S)-leucyl-N-methyl-(S)-leucyl-N-methyl-(S)-valin-tert-butylester 
• 109745-94-0 N-(Benzyloxycarbonyl)tetrapeptidsaeure 
• 109745-94-0 N-(tert-Butoxycarbonyl)-(R)-alanyl-N-Methyl-(S)-leucyl-N-methyl-(S)-leucyl-N-methyl-(S)-valin 

Relevant articles and documents

SYNTHESIS OF TWO LINEAR OCTAPEPTIDE FRAGMENTS OF CYCLOSPORIN BY STEPWISE AND FRAGMENT CONDENSATION STRATEGIES

The octapeptide Z-(Me)Leu-Val-(Me)Leu-Ala-D-Ala-(Me)Leu-(Me)Leu-(Me)Val-O(t-Bu) was prepared by stepwise elongation starting from H-(Me)Val-O(t-Bu).Diphenylphosphinic mixed anhydrides were preferentially used throughout as they gave high yields of optical

Amino Acids and Peptides, 63. - Peptide Synthesis via N- or O-Activation of Amino Acids with 1,2-Dihydro-4,6-dimethyl-2-thioxo-3-pyridinecarbonitrile. - Synthesis of the 8-11 Tetrapeptide Sequence of Cyclosporin

Peptides and N-methyl peptides have been prepared in high yields and nearly free of racemisation via N-activation (Scheme 1) or O-activation (Scheme 2) of N-acylamino acids and N-acyl-N-methylamino acids, respectively, by 1,2-dihydro-4,6-dimethyl-2-thioxo