1174540-28-3

Basic information

• Product Name: 2-((R)-(1-(1,1-dioxohexahydro-1λ6-thiopyran-4-yl)methylamino)ethyl)-3-(4-chlorophenyl)pyrido[2,3d]pyrimidin-4(3H)-one
• CAS NO: 1174540-28-3
• Molecular Weight: 446.958
• Mol File: 1174540-28-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-((R)-(1-(1,1-dioxohexahydro-1λ6-thiopyran-4-yl)methylamino)ethyl)-3-(4-chlorophenyl)pyrido[2,3d]pyrimidin-4(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-((R)-(1-(1,1-dioxohexahydro-1λ6-thiopyran-4-yl)methylamino)ethyl)-3-(4-chlorophenyl)pyrido[2,3d]pyrimidin-4(3H)-one(1174540-28-3)
• EPA Substance Registry System: 2-((R)-(1-(1,1-dioxohexahydro-1λ6-thiopyran-4-yl)methylamino)ethyl)-3-(4-chlorophenyl)pyrido[2,3d]pyrimidin-4(3H)-one(1174540-28-3)

Safety Data

• Hazardous Substances Data: 1174540-28-3(Hazardous Substances Data)

Upstream product

• 494210-61-6 1,1-dioxo-hexahydro-1λ⁶-thiopyran-4-carbaldehyde 
• 1174540-27-2 (+)-2-(1-(R)-aminoethyl)-3-(4-chlorophenyl)pyrido[2,3-d]pyrimidin-4(3H)-one 
• 5345-47-1 2-aminopyridin-3-carboxylic acid 
• 1174540-25-0 C₁₅H₁₁ClN₆O 
• 1174540-26-1 2-(1-aminoethyl)-3-(4-chlorophenyl)pyrido[2,3-d]pyrimidin-4(3H)-one 
• 1174540-23-8 3-(4-chlorophenyl)-2-ethylpyrido[2,3-d]pyrimidin-4(3H)-one 
• 1174540-24-9 2-(1-chloroethyl)-3-(4-chlorophenyl)pyrido[2,3-d]pyrimidin-4(3H)-one 
• 56329-05-6 2-amino-N-(4-chlorophenyl)nicotinamide 
• 106-47-8 4-chloro-aniline 
• 50675-19-9 4-thianylcarbaldehyde 

Downstream Products

• 1174540-21-6 (R)-2-(N-1-(3-(4-chlorophenyl)pyrido[2,3-d]pyrimidin-4(3H)-one)-N-(1,1-dioxohexahydro-1λ6-thiopyran-4-yl)methyl)-2-(3-fluoro-4-(trifluoromethyl)phenyl)acetamide 
• 1262797-01-2 C₃₀H₂₇ClF₄N₄O₄S 

Relevant articles and documents

Practical syntheses of a CXCR3 antagonist

Two new, reliable syntheses of a pyrido[2,3-d]- pyrimidine inhibitor of the CXCR3 receptor are described. A nine-step synthesis of the CXCR3 inhibitor (1) from 2-aminonicotinic acid was demonstrated on a multikilogram scale and incorporates a classic reso