1174761-19-3

Basic information

• Product Name: N-(tert-butoxycarbonyl)-α-(phenylsulfonyl)-2-fluorobenzylamine
• Synonyms: N-(tert-butoxycarbonyl)-α-(phenylsulfonyl)-2-fluorobenzylamine
• CAS NO: 1174761-19-3
• Molecular Weight: 365.426
• Mol File: 1174761-19-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(tert-butoxycarbonyl)-α-(phenylsulfonyl)-2-fluorobenzylamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(tert-butoxycarbonyl)-α-(phenylsulfonyl)-2-fluorobenzylamine(1174761-19-3)
• EPA Substance Registry System: N-(tert-butoxycarbonyl)-α-(phenylsulfonyl)-2-fluorobenzylamine(1174761-19-3)

Safety Data

• Hazardous Substances Data: 1174761-19-3(Hazardous Substances Data)

Upstream product

• 4248-19-5 tert-butyl carbazate 
• 873-55-2 sodium benzenesulfonate 
• 446-52-6 2-Fluorobenzaldehyde 

Downstream Products

• 1207874-02-9 tert-butyl (1S,2S)-(1-(2-fluorophenyl)-2-nitropropyl)carbamate 
• 1207874-03-0 tert-butyl (1R,2R)-(1-(2-fluorophenyl)-2-nitropropyl)carbamate 
• 709665-72-5 methyl 2-((tert-butoxycarbonyl)amino)-2-(2-fluorophenyl)acetate 
• 153903-21-0 N-(tert-butyloxycarbonyl)-2-fluorobenzylamine 
• 161330-30-9 2-((tert-butoxycarbonyl)amino)-2-(2-fluorophenyl)acetic acid 
• 1174761-17-1 (R)-tert-butyl (1-(2-fluororophenyl)-2-nitroethyl)carbamate 
• 1174761-16-0 (S)-tert-butyl (1-(2-fluororophenyl)-2-nitroethyl)carbamate 

Relevant articles and documents

One-pot synthesis of α-amino acids from imines through CO2 incorporation: An alternative method for strecker synthesis

Itas a gas: A novel one-pot process for the synthesis of α-amino acids from imine equivalents using CO2 gas as a carbon source has been developed. This reaction was made possible by the reagent combination of TMSSnBu3 and CsF (see scheme). Three successive reactions (imine formation, stannylation, and carboxylation) proceeded in the same flask under these conditions to give products in up to 79 % yield. Boc=tert-butoxycarbonyl, TMS=trimethylsilyl.