709665-72-5

Basic information

• Product Name: methyl 2-((tert-butoxycarbonyl)amino)-2-(2-fluorophenyl)acetate
• Synonyms: methyl 2-((tert-butoxycarbonyl)amino)-2-(2-fluorophenyl)acetate
• CAS NO: 709665-72-5
• Molecular Weight: 283.3
• Mol File: 709665-72-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: methyl 2-((tert-butoxycarbonyl)amino)-2-(2-fluorophenyl)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-((tert-butoxycarbonyl)amino)-2-(2-fluorophenyl)acetate(709665-72-5)
• EPA Substance Registry System: methyl 2-((tert-butoxycarbonyl)amino)-2-(2-fluorophenyl)acetate(709665-72-5)

Safety Data

• Hazardous Substances Data: 709665-72-5(Hazardous Substances Data)

Upstream product

• 186581-53-3 diazomethane 
• 124-38-9 carbon dioxide 
• 1174761-19-3 N-(tert-butoxycarbonyl)-α-(phenylsulfonyl)-2-fluorobenzylamine 
• 4248-19-5 tert-butyl carbazate 
• 446-52-6 2-Fluorobenzaldehyde 
• 195070-57-6 (±)-2-(2-fluorophenyl)glycine methyl ester hydrochloride 
• 24424-99-5 di-tert-butyl dicarbonate 
• 161330-30-9 2-((tert-butoxycarbonyl)amino)-2-(2-fluorophenyl)acetic acid 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 1358791-63-5 N-(tert-butoxycarbonyl)-α-(tributylstannyl)-2-fluorobenzylamine 

Downstream Products

• 709665-79-2 4-(2-fluorophenyl)-5,5-dimethyloxazolidin-2-one 
• 1456505-10-4 4-(4-(2-fluorophenyl)-5,5-dimethyl-2-oxooxazolidin-3-yl)-N-(quinolin-8-yl)benzamide 
• 709665-75-8 tert-butyl (1-(2-fluorophenyl)-2-hydroxy-2-methylpropyl)carbamate 

Relevant articles and documents

OXAZOLIDINONE COMPOUNDS AND DERIVATIVES THEREOF

Compounds of Formula (I) and Formula (II) are useful inhibitors of tankyrase. Compounds of Formula (I) and Formula (II) have the following structure: where the definitions of the variables are provided herein.

One-pot synthesis of α-amino acids from CO2 using a bismetal reagent with Si-B bond

In the presence of 1.1 equiv of PhMe2Si-Bpin, 5 equiv of CsF, and 20 mol % of TsOH·H2O, precursors of N-Boc-imines can be converted into the corresponding α-aryl or α-alkenyl glycine derivatives under gaseous CO2 in moderate-to-high yields with a single operation. α-Isobutenyl glycine thus obtained can be further derivatized into various types of α-amino acids including N-Boc-leucine, serine, and glycine derivatives in short steps.