117710-90-4Relevant articles and documents
TfOH-Promoted Reaction of 2,4-Diaryl-1,1,1-Trifluorobut-3-yn-2-oles with Arenes: Synthesis of 1,3-diaryl-1-CF3-indenes and versatility of the reaction mechanisms
Zerov, Aleksey V.,Kazakova, Anna N.,Boyarskaya, Irina A.,Panikorovskii, Taras L.,Suslonov, Vitalii V.,Khoroshilova, Olesya V.,Vasilyev, Aleksander V.
, (2018)
The TfOH-mediated reactions of 2,4-diaryl-1,1,1-trifluorobut-3-yn-2-oles (CF3-substituted diaryl propargyl alcohols) with arenes in CH2Cl2 afford 1,3-diaryl-1-CF3-indenes in yields up to 84%. This new process for synthesis of such CF3-indenes is complete
Bimetallic copper and zinc-catalyzed oxidative cycloaddition of 3-aminopyridazines and nitriles: A direct synthesis of 1,2,4-triazolo[1,5-: B] pyridazines via C-N and N-N bond-forming process
Mu, Qiu-Chao,Lv, Ji-Yuan,Chen, Mu-Yi,Bai, Xing-Feng,Chen, Jing,Xia, Chun-Gu,Xu, Li-Wen
, p. 37208 - 37213 (2017)
One-pot formation of the 1,2,4-triazolo[1,5-b]pyridazine nucleus and its derivatives is presented in this manuscript, in which the desired targets are offered easily via cooperative Cu(i) and Zn(ii)-catalyzed tandem C-N addition and subsequent I2/KI-mediated intramolecular oxidative N-N bond formation.
Copper(I) alkoxide-catalyzed alkynylation of trifluoromethyl ketones
Motoki, Rie,Kanai, Motomu,Shibasaki, Masakatsu
, p. 2996 - 3000 (2007)
A general method for direct alkynylation of trifluoromethyl ketones was developed by using CuO'Bu-xantphos or phenanthroline complexes as catalysts. The ligands significantly enhanced the catalyst activity. In addition, KOTf, generated in the catalyst pre
Catalytic Synthesis of Trifluoromethylated Allenes, Indenes, Chromenes, and Olefins from Propargylic Alcohols in HFIP
No?l, Florent,Vukovi?, Vuk D.,Yi, Jing,Richmond, Edward,Kravljanac, Pavle,Moran, Joseph
, p. 15926 - 15947 (2019/12/25)
A general method to access CF3-substituted allenes from propargylic alcohols under Lewis acid catalysis in 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP) as solvent is described. By tuning the reaction time and temperature, the obtained allenes rearr
