117740-74-6Relevant articles and documents
Structure and activity relationships of novel uracil derivatives as topical anti-inflammatory agents
Isobe, Yoshiaki,Tobe, Masanori,Inoue, Yoshifumi,Isobe, Masakazu,Tsuchiya, Masami,Hayashi, Hideya
, p. 4933 - 4940 (2007/10/03)
In order to create novel, topical anti-inflammatory compounds exhibiting more potent activities than lead compound CX-659S (1), we designed and synthesized various derivatives of 1 focusing on the uracil N(1)- and N(3)-substituents, and evaluated their an
8-Azaxanthines alkylaminoalkyl or heterocyclylalkyl-substituted on the triazole ring, the salts thereof which are physiologically acceptable, their pharmaceutical compositions having antibronchospastic acivity, and the process for preparing the same
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, (2008/06/13)
The present invention relates to 8-azaxanthine derivatives having the general formula: wherein R1 = H; CnH2n+1wherein n = 1 or 3;, R2 = CnH2n+1wherein n = 1 or 5; or C6H5/s