117839-38-0

Basic information

• Product Name: 4-Quinolinecarboxaldehyde, 2-phenyl-
• CAS NO: 117839-38-0
• Molecular Formula: C16H11NO
• Molecular Weight: 233.269
• Mol File: 117839-38-0.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 4-Quinolinecarboxaldehyde, 2-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Quinolinecarboxaldehyde, 2-phenyl-(117839-38-0)
• EPA Substance Registry System: 4-Quinolinecarboxaldehyde, 2-phenyl-(117839-38-0)

Safety Data

• Hazardous Substances Data: 117839-38-0(Hazardous Substances Data)

Upstream product

• 29268-33-5 4-hydroxymethyl-2-phenylquinoline 
• 4789-76-8 4-methyl-2-phenylquinoline 
• 132-60-5 cinchophen 
• 52562-19-3 2-isopropenylaniline 
• 98-88-4 benzoyl chloride 
• 106012-41-3 N-[2-(1-methylethenyl)phenyl]benzamide 
• 491-35-0 C₆H₄NCH₂CHCCH₂ 
• 591-51-5 phenyllithium 
• 612-96-4 2-Phenylquinoline 
• 4546-48-9 methyl 2-phenylquinoline-4-carboxylate 

Downstream Products

• 132-60-5 cinchophen 
• 30836-70-5 4-(Diphenylmethyl)-2-phenylquinoline 
• 29268-33-5 4-hydroxymethyl-2-phenylquinoline 
• 47492-97-7 N,N-diethyl-N'-(2-phenyl-[4]quinolylmethyl)-propanediyldiamine 

Relevant articles and documents

Photoredox-Catalyzed Redox-Neutral Minisci C?H Formylation of N-Heteroarenes

We report a protocol for redox-neutral Minisci C?H formylation of N-heteroarenes using 1,3-dioxoisoindolin-2-yl 2,2-diethoxyacetate as a formyl equivalent at room temperature. This scalable benchtop protocol offers a distinct advantage over traditional reductive carbonylation and Minisci C?H formylation methods in not requiring the use of carbon monoxide, pressurized gas, a stoichiometric reductant, or a stoichiometric oxidant. (Figure presented.).

Transition-Metal-Free Oxidation of Benzylic C-H Bonds of Six-Membered N-Heteroaromatic Compounds

A novel oxidation of benzylic C-H bonds for the synthesis of diverse six-membered N-heteroaromatic aldehydes and ketones has been developed. The obvious advantages of this approach are the simple operation, mild reaction conditions, and without use of toxic reagent and transition metal. The present method should provide a useful access for the synthesis and modification of N-heterocycles.

COMPOUNDS FOR TREATMENT OF GLIOBLASTOMA

The present invention relates to compounds and methods for the treatment of glioblastoma, as well as to a pharmaceutical composition comprising said compounds. More specifically the invention relates to substituted quinoline derivatives having the formula (I), (II) or (III), and a pharmaceutical composition comprising said compounds for the treatment of cancer. (Formulae (I), (II), (III))