118485-40-8

Basic information

• Product Name: (E)-2-benzylidene-3-methyl-2,3-dihydro-1H-inden-1-one
• Synonyms: (E)-2-benzylidene-3-methyl-2,3-dihydro-1H-inden-1-one
• CAS NO: 118485-40-8
• Molecular Weight: 234.298
• Mol File: 118485-40-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (E)-2-benzylidene-3-methyl-2,3-dihydro-1H-inden-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-2-benzylidene-3-methyl-2,3-dihydro-1H-inden-1-one(118485-40-8)
• EPA Substance Registry System: (E)-2-benzylidene-3-methyl-2,3-dihydro-1H-inden-1-one(118485-40-8)

Safety Data

• Hazardous Substances Data: 118485-40-8(Hazardous Substances Data)

Upstream product

• 6072-57-7 3-methylindanone 
• 100-52-7 benzaldehyde 
• 2142-64-5 1-(2-ethylphenyl)ethanone 
• 76118-05-3 2-ethylbenzoyl chloride 

Downstream Products

• 130289-61-1 C₂₃H₂₄O 
• 26129-30-6 trans-2-Benzyliden-1-diphenylmethylen-3-methylindan 
• 130289-63-3 C₂₂H₂₂O 
• 118485-20-4 C₃₀H₂₃ClN₂O 
• 118485-19-1 C₃₁H₂₆N₂O₂ 
• 118485-18-0 C₃₀H₂₄N₂O 
• 135998-46-8 C₂₄H₁₉NO₂ 

Relevant articles and documents

Light-enabled, AlCl3-catalyzed regioselective intramolecular nucleophilic addition of non-nucleophilic alkyls to alkynes

Light-enabled, AlCl3-catalyzed regioselective intramolecular nucleophilic cyclization of alkynes using non-nucleophilic alkyls as the nucleophile is reported. Upon photoexcitation, o-alkylphenyl alkynyl ketones can be transferred into (E)-photoenols. Thus, a nucleophilic methylene is formed from the non-nucleophilic alkyl. An AlCl3 catalyst can stabilize the (E)-photoenol intermediate and facilitate further intramolecular nucleophilic cyclization. DFT calculations indicated that the AlCl3-catalyzed cyclization is the regioselectivity determining step.