6072-57-7Relevant articles and documents
Nickel-Catalyzed Ring Expansion of Cyclobutanones towards Indanones
Chen, Tengyun,Wu, Yunkai,Han, Peilin,Gao, Jiqiang,Wu, Yuanqi,Zhao, Jinbo,Liang, Haotian,Liu, Yongsheng,Liu, Yu
, (2022/01/13)
Despite recent advances in catalytic ring-opening/cross-coupling process of o-halogen tethered phenylcyclobutanones with other partners, single-component ring expansion of such precursors towards 3-methylindanones has not been disclosed. We present herein a nickel catalyzed C?C bond reconstruction sequence of o-bromophenylcyclobutanones using H2O as hydrogen donor, leading to a series of indanones, which can be further converted into other benzene-fused cyclic compounds.
Preparation method of indanone compound
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Paragraph 0035-0081, (2021/08/07)
The invention provides a preparation method of a hydrindone compound, and belongs to the technical field of compound synthesis. The method comprises the following steps: under the action of a nickel catalyst, a ligand, bis(pinacolato)diboron, alkali and water, reacting o-bromophenyl cyclobutanone of a formula 1 structure in a solvent at 70-90 DEG C for 12-24 hours, and separating and purifying a product after the reaction is finished to obtain the indanone compound of the formula I structure. The method is simple, raw materials are easy to obtain, experimental operation is simple and convenient, and the yield of the prepared product is moderate.
One-pot multicomponent synthesis and antimicrobial evaluation of novel tricyclic indenopyrimidine-2-amines
Kaur, Navjot,Singh, Pratibha,Kaur, Pawandeep,Yadav, Ajar Nath,Singh, Karan
, p. 3622 - 3631 (2020/08/19)
The synthesis of novel tricyclic indenopyrimidine-2-amines from 3,3-dimethyl-/3-methyl-2H-indanones has achieved by base-catalyzed one-pot three-component reaction. The desired products are formed within 10 hours after addition at reflux temperature. This