118494-97-6

Basic information

• Product Name: ()-7,7'-bis-benzyloxy-[1,1']-binaphthalene-2,2'-diol
• CAS NO: 118494-97-6
• Molecular Weight: 498.578
• Mol File: 118494-97-6.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: ()-7,7'-bis-benzyloxy-[1,1']-binaphthalene-2,2'-diol(CAS DataBase Reference)
• NIST Chemistry Reference: ()-7,7'-bis-benzyloxy-[1,1']-binaphthalene-2,2'-diol(118494-97-6)
• EPA Substance Registry System: ()-7,7'-bis-benzyloxy-[1,1']-binaphthalene-2,2'-diol(118494-97-6)

Safety Data

• Hazardous Substances Data: 118494-97-6(Hazardous Substances Data)

Upstream product

• 118495-07-1 7-(benzyloxy)-2-naphthol 
• 75-64-9 tert-butylamine 
• 7260-11-9 phenyl 2-hydroxy-3-naphthoate 
• 582-17-2 2,7-Dihydroxynaphthalene 
• 896427-74-0 6-[3,5-bis(trifluoromethyl)phenyl]naphthalen-2-ol 
• 65283-60-5 (R)-6,6'-dibromo-1,1'-binaphth-2-ol 
• 135-19-3 β-naphthol 
• 18531-94-7 (R)-1,1'-Bi-2-naphthol 
• 118494-97-6 (R)-7,7-bis(benzyloxy)-2,2'-dihydroxy-1,1'-binaphthyl 
• 15231-91-1 6-bromo-naphthalen-2-ol 
• 118494-97-6 ()-7,7'-bis-benzyloxy-[1,1']-binaphthalene-2,2'-diol 
• 171192-51-1 7,7'-Bis-benzyloxy-3,3'-dibromo-[1,1']binaphthalenyl-2,2'-diol 
• 171192-58-8 6-(benzyloxy)-2-bromo-3-(methoxymethoxy)naphthalene 
• 171192-59-9 7-(benzyloxy)-3-bromonaphthalen-2-ol 

Downstream Products

• 118494-98-7 2-(7,7'-Bis-benzyloxy-2'-diethylcarbamoylmethoxy-[1,1']binaphthalenyl-2-yloxy)-N,N-diethyl-acetamide 
• 118494-97-6 (R)-7,7-bis(benzyloxy)-2,2'-dihydroxy-1,1'-binaphthyl 
• 118494-97-6 (S)‐7,7′‐bis(benzyloxy)‐[1,1′‐binaphthalene]‐2,2′‐diol 
• 1027004-26-7 C₃₆H₃₀O₅ 
• 123675-57-0 (R)-(-)-7,7'-bis(benzyloxy)-2,2'-dimethoxy-1,1'-binaphthyl 
• 123675-57-0 (S)-(+)-7,7'-Bis(benzyloxy)-2,2'-dimethoxy-1,1'-binaphthyl 
• 123675-57-0 (R)-(-)-7,7'-Bis(benzyloxy)-2,2'-dimethoxy-1,1'-binaphthyl 
• 118495-03-7 C₄₄H₄₄O₈ 

Relevant articles and documents

Catalytic enantioselective coupling of 2-naphthols by new chiral oxovanadium complexes bearing a self accelerating functional group

New chiral oxovanadium complexes containing an extra phenolic hydroxyl group were found to enhance the catalytic enantioselective coupling of 2-naphthols in moderate to good enantioselectivity.

Enantioselective iron/bisquinolyldiamine ligand‐catalyzed oxidative coupling reaction of 2‐naphthols

An iron‐catalyzed asymmetric oxidative homo‐coupling of 2‐naphthols for the synthesis of 1,1′‐Bi‐2‐naphthol (BINOL) derivatives is reported. The coupling reaction provides enantioenriched BINOLs in good yields (up to 99%) and moderate enantioselectivities (up to 81:19 er) using an iron‐complex generated in situ from Fe(ClO4)2 and a bisquinolyldiamine ligand [(1R,2R)‐N1,N2‐di(quinolin‐8‐yl)cyclohexane‐1,2‐diamine, L1]. A number of ligands (L2–L8) and the analogs of L1, with various substituents and chiral backbones, were synthesized and examined in the oxidative coupling reactions.

Linker-oriented design of binaphthol derivatives for optical resolution using lipase-catalyzed reaction

(Chemical Equation Presented) Candida antarctica lipase B (CAL-B) is one the most frequently used enzymes in organic synthesis for the preparation of optically active alcohols. However, it has not been used for the optical resolution of (±)-2,2′-binaphthol. We established an efficient linker-oriented design of 2,2′-binaphthol derivatives that is appropriate for optical resolution using CAL-B-catalyzed hydrolysis reaction. Methyl 4-(1-(6-bromo-2-methoxymethoxynaphthalen-1-yl)-6-bromonaphthalen-2-yloxy) butanoate was hydrolyzed by CAL-B to afford a corresponding acid with excellent enantioselectivity (E > 200). Two types of optically active binaphthol derivatives, 1-(2-hydroxy-6-(naphthalen-1-yl)naphthalen-1-yl)-6-(naphthalen-1- yl)naphthalen-2-ol and 6-butyl-1-(6-butyl-2-hydroxynaphthalen-1-yl)naphthalen-2- ol, were prepared by this chemoenzymatic reaction protocol and were used as chiral templates for symmetric reactions.

Novel diphosphine compound, production intermediate thereof, transition metal complex containing the compound as ligand and asymmetric hydrogenation catalyst containing the complex

The present invention provides a novel phosphine compound, specifically to provide a novel phosphine compound useful as a ligand for the above catalysts, in particular, a novel catalyst having an excellent performance (chemical selectivity, enantio-select