1186678-00-1

Basic information

• Product Name: (E)-1-bromo-2-[1-(4-fluorophenyl)-2-methoxyethenyl]benzene
• CAS NO: 1186678-00-1
• Molecular Weight: 307.162
• Mol File: 1186678-00-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-1-bromo-2-[1-(4-fluorophenyl)-2-methoxyethenyl]benzene(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-1-bromo-2-[1-(4-fluorophenyl)-2-methoxyethenyl]benzene(1186678-00-1)
• EPA Substance Registry System: (E)-1-bromo-2-[1-(4-fluorophenyl)-2-methoxyethenyl]benzene(1186678-00-1)

Safety Data

• Hazardous Substances Data: 1186678-00-1(Hazardous Substances Data)

Upstream product

• 20763-19-3 (methoxymethylene)triphenylphosphorane 
• 573-46-6 (2-bromophenyl)(4-fluorophenyl)methanone 

Relevant articles and documents

Synthesis of 1,3-Diaryl-2-methoxyindenes by hydriodic acid-catalyzed cyclization of Aryl[2-(1-aryl-2-methoxyvinyl)phenyl]methanols

An efficient two-step method for the synthesis of 1,3-diaryl-2- methoxyindenes from 1-(1-aryl-2-methoxyvinyl)-2-bromobenzenes has been developed. Thus, the reaction of 2-(1-aryl-2-methoxyvinyl)phenyllithiums, generated in situ by halogen-lithium exchange between 1-(1-aryl-2-methoxyvinyl)- 2-bromobenzenes and butyllithium, with aromatic aldehydes gives aryl[2-(1-aryl-2-methoxyvinyl)phenyl]methanols, which in turn are treated with a catalytic amount of concentrated hydriodic acid to afford the corresponding 1,3-diaryl-2-methoxyindenes in reasonable yields.