118758-56-8 Usage
General Description
Boc-pyrrolidin-2-yl-acetic acid ethyl ester is a chemical compound used in organic synthesis and pharmaceutical research. It is a derivative of pyrrolidine and acetic acid, and is often used as a building block in the synthesis of various drugs and pharmaceuticals. The "Boc" in the name refers to the tert-butoxycarbonyl protecting group, which is commonly used in organic chemistry to protect amine groups. The ethyl ester group in the compound makes it more lipophilic and increases its solubility in organic solvents, making it easier to handle and manipulate in chemical reactions. Overall, Boc-pyrrolidin-2-yl-acetic acid ethyl ester is a versatile chemical used in the production of pharmaceuticals and has potential applications in drug discovery and development.
Check Digit Verification of cas no
The CAS Registry Mumber 118758-56-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,8,7,5 and 8 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 118758-56:
(8*1)+(7*1)+(6*8)+(5*7)+(4*5)+(3*8)+(2*5)+(1*6)=158
158 % 10 = 8
So 118758-56-8 is a valid CAS Registry Number.
118758-56-8Relevant articles and documents
Synthesis of tylocrebrine and related phenanthroindolizidines by VOF 3-mediated oxidative aryl-alkene coupling
Niphakis, Micah J.,Georg, Gunda I.
supporting information; experimental part, p. 196 - 199 (2011/03/19)
A highly convergent strategy to prepare phenanthroindolizidines is reported involving three consecutive C-C coupling reactions. This sequence features a novel VOF3-mediated aryl-alkene coupling in the final step, which enables regioselective preparation of C5-substituted phenanthroindolizidines for the first time. This strategy has been applied to the synthesis of eight natural and unnatural members in this class to investigate the scope of this chemistry and to explore structure-activity relationships.
Oxidative Generation of N-Acyliminium Ions from N-1-(Tributylstannyl)alkyl Carboxamides and Carbamates and Their Reactions with Carbon Nucleophiles
Narasaka, Koichi,Kohno, Yasushi
, p. 3456 - 3463 (2007/10/02)
Oxidation of N-1-(tributylstannyl)alkyl carboxamides and carbamates with ammonium hexanitratocerate (IV) or ferrocenium hexafluorophosphate generates their N-acyliminium ions by the elimination of tributylstannyl radical under mild reaction conditions.The
