118824-97-8

Basic information

• Product Name: Ethanone, 1-(4-hydroxy-2-methoxy-3-methylphenyl)-
• CAS NO: 118824-97-8
• Molecular Formula: C10H12O3
• Molecular Weight: 180.203
• Mol File: 118824-97-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Ethanone, 1-(4-hydroxy-2-methoxy-3-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-(4-hydroxy-2-methoxy-3-methylphenyl)-(118824-97-8)
• EPA Substance Registry System: Ethanone, 1-(4-hydroxy-2-methoxy-3-methylphenyl)-(118824-97-8)

Safety Data

• Hazardous Substances Data: 118824-97-8(Hazardous Substances Data)

Usage

General Description

Ethanone, 1-(4-hydroxy-2-methoxy-3-methylphenyl)- is a chemical compound that belongs to the class of organic compounds known as acetophenones. It is a white crystalline solid with a molecular formula C11H14O3 and a molecular weight of 194.23 g/mol. Ethanone, 1-(4-hydroxy-2-methoxy-3-methylphenyl)- is a derivative of acetophenone with a hydroxy and methoxy substituent at the 4- and 2- positions, respectively, on the phenyl ring. It is commonly used in the pharmaceutical industry as a building block for the synthesis of various drugs and as an intermediate in organic chemistry reactions. Additionally, it exhibits antioxidant and anti-inflammatory properties, which make it a potential candidate for medical and skincare applications.

Upstream product

• 5673-07-4 2,6-dimethoxytoluene 
• 75-36-5 acetyl chloride 
• 73640-74-1 1-(4-(benzyloxy)-2-hydroxy-3-methylphenyl)ethanone 
• 10139-84-1 1-(2,4-dihydroxy-3-methylphenyl)ethanone 
• 608-25-3 2-methylbenzene-1,3-diol 
• 118824-96-7 4'-Benzyloxy-2'-methoxy-3'-methylacetophenone 

Downstream Products

• 60512-80-3 2′,4′-dimethoxy-3′-methylacetophenone 
• 65117-54-6 2-Methoxy-3-methyl-5-nitro-1,4-hydroquinone 
• 118824-98-9 4'-Hydroxy-2'-methoxy-3'-methyl-5'-nitroacetophenone 

Relevant articles and documents

Iridium-Catalyzed C(sp3)?H Addition of Methyl Ethers across Intramolecular Carbon–Carbon Double Bonds Giving 2,3-Dihydrobenzofurans

Intramolecular addition of an O-methyl C(sp3)?H bond across a carbon-carbon double bond occurs in the iridium-catalyzed reaction of methyl 2-(propen-2-yl)phenyl ethers. The Ir/(S)-DTBM-SEGPHOS catalyst promotes the reaction efficiently in toluene at 110–135 °C to afford 3,3-dimethyl-2,3-dihydrobenzofurans. Enantioselective C(sp3)?H addition is achieved in the reaction of methyl 2-(1-siloxyethenyl)phenyl ethers, affording enantioenriched 3-hydroxy-2,3-dihydrobenzofuran derivatives with up to 96% ee. (Figure presented.).

Synthesis of Indolin-2-ones (Oxindoles) Related to Mitomycin A

Oxindoles (indolin-2-ones) containing the functionality of the first two rings of the mytomicin A structure have been synthesized.Attempts to employ the oxindole grouping to construct the third ring were unsuccessful because of the resistance of the oxindole group or its derivatives towards nucleophilic attack.An unusual methylation of 3-methyl-5-nitrobenzene-1,2,4-triol to give the (E)-3,6-dihydroxy-2-methyl-1,4-benzoquinone 4-methoxyimine N-oxide is noted.A novel indole formation is described.