73640-74-1Relevant articles and documents
2-AMINOPYRIDINE DERIVATIVE
-
Page/Page column 15; 23, (2010/11/25)
The invention relates to a compound useful as remedies or preventives for IKK2-related inflammatory diseases or autoimmune diseases, or that is, a 2-aminopyrimidine derivative having a 2-hydroxyphenyl group at the 6-position thereof and having a saturated
Synthesis of Indolin-2-ones (Oxindoles) Related to Mitomycin A
Raphael, Ralph A.,Ravenscroft, Paul
, p. 1823 - 1828 (2007/10/02)
Oxindoles (indolin-2-ones) containing the functionality of the first two rings of the mytomicin A structure have been synthesized.Attempts to employ the oxindole grouping to construct the third ring were unsuccessful because of the resistance of the oxindole group or its derivatives towards nucleophilic attack.An unusual methylation of 3-methyl-5-nitrobenzene-1,2,4-triol to give the (E)-3,6-dihydroxy-2-methyl-1,4-benzoquinone 4-methoxyimine N-oxide is noted.A novel indole formation is described.