1191057-89-2

Basic information

• Product Name: (R)-N-(cyano(4-fluorophenyl)methyl)-N-methylacetamide
• Synonyms: (R)-N-(cyano(4-fluorophenyl)methyl)-N-methylacetamide
• CAS NO: 1191057-89-2
• Molecular Weight: 206.22
• Mol File: 1191057-89-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (R)-N-(cyano(4-fluorophenyl)methyl)-N-methylacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-N-(cyano(4-fluorophenyl)methyl)-N-methylacetamide(1191057-89-2)
• EPA Substance Registry System: (R)-N-(cyano(4-fluorophenyl)methyl)-N-methylacetamide(1191057-89-2)

Safety Data

• Hazardous Substances Data: 1191057-89-2(Hazardous Substances Data)

Upstream product

• 370554-92-0 2-(4-fluorophenyl)-2-(methylamino)acetonitrile 
• 122-79-2 Phenyl acetate 
• 459-57-4 4-fluorobenzaldehyde 
• 7677-24-9 trimethylsilyl cyanide 
• 1191057-85-8 (E)-N-(2,4-difluorobenzylidene)propan-1-amine 
• 17972-08-6 N-[(1E)-(2-chlorophenyl)methylene]methanamine 
• 82605-86-5 (E)-N-(4-fluorobenzylidene)ethanamine 
• 64-19-7 acetic acid 

Relevant articles and documents

Racemase activity of B. cepacia lipase leads to dual-function asymmetric dynamic kinetic resolution of α-aminonitriles

Applaudable promiscuity: Racemase-type activity discovered for B. cepacia lipase with N-substituted α-aminonitriles is proposed to involve a C-C bond-breaking/forming mechanism in the hydrolase site of the enzyme, as supported by experimental data and calculations. This promiscuous activity in combination with the transacylation activity of the enzyme enabled the asymmetric synthesis of N-methyl α-aminonitrile amides in high yield (see scheme). Copyright