1194550-56-5 Usage
Description
5,7-dichloro-2-trityl-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid is a complex organic compound with a unique molecular structure that features a trityl group and two chlorine atoms. 5,7-dichloro-2-trityl-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid has potential applications in various fields due to its chemical properties and reactivity.
Uses
Used in Pharmaceutical Industry:
5,7-dichloro-2-trityl-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid is used as a key intermediate in the synthesis of novel compounds with potent biological activities. Specifically, it has been found to be useful in the preparation of LFA-1/ICAM-1 Antagonist SAR 1118, which is an important compound for the development of ophthalmic solutions.
Used in Ophthalmology:
In the field of ophthalmology, 5,7-dichloro-2-trityl-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid is used as a precursor for the development of ophthalmic solutions, such as SAR 1118. 5,7-dichloro-2-trityl-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid serves as a LFA-1/ICAM-1 Antagonist, which helps in treating dry eye syndrome by reducing inflammation and improving the overall health of the ocular surface.
Check Digit Verification of cas no
The CAS Registry Mumber 1194550-56-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,9,4,5,5 and 0 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1194550-56:
(9*1)+(8*1)+(7*9)+(6*4)+(5*5)+(4*5)+(3*0)+(2*5)+(1*6)=165
165 % 10 = 5
So 1194550-56-5 is a valid CAS Registry Number.
1194550-56-5Relevant articles and documents
LFA-1 INHIBITOR AND POLYMORPH THEREOF
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, (2014/02/16)
Methods of preparation and purification of a compound, intermediates thereof, a polymorph thereof, and related compounds are disclosed. Formulations and uses thereof in the treatment of LFA -1 mediated diseases are also disclosed.
