119595-73-2

Basic information

• Product Name: L-Glutamic acid, N-(9-phenyl-9H-fluoren-9-yl)-, 1-(1,1-dimethylethyl) 5-methyl ester
• CAS NO: 119595-73-2
• Molecular Formula: C29H31NO4
• Molecular Weight: 457.569
• Mol File: 119595-73-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: L-Glutamic acid, N-(9-phenyl-9H-fluoren-9-yl)-, 1-(1,1-dimethylethyl) 5-methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Glutamic acid, N-(9-phenyl-9H-fluoren-9-yl)-, 1-(1,1-dimethylethyl) 5-methyl ester(119595-73-2)
• EPA Substance Registry System: L-Glutamic acid, N-(9-phenyl-9H-fluoren-9-yl)-, 1-(1,1-dimethylethyl) 5-methyl ester(119595-73-2)

Safety Data

• Hazardous Substances Data: 119595-73-2(Hazardous Substances Data)

Upstream product

• 71432-55-8 2-tert-butyl-1,3-diisopropylisourea 
• 119595-72-1 L-N-(9-(9-phenylfluorenyl))glutamic acid γ-methylester 
• 50867-21-5 N,N'-dicylohexylcarbamimidic acid tert-butyl ester 
• 98946-18-0 tert-Butyl 2,2,2-trichloroacetimidate 
• 186581-53-3 diazomethane 
• 1499-55-4 L-glutamic acid 5-methyl ester 
• 55135-66-5 9-bromo-9-phenyl-9H-fluorene 

Downstream Products

• 1027671-15-3 (S)-2-Pentanoyl-4-(9-phenyl-9H-fluoren-9-ylamino)-pentanedioic acid 5-tert-butyl ester 1-methyl ester 
• 119595-84-5 tert-butyl (2S)-5-hydroxy-2-(N-(9-(9-phenylfluorenyl))amino)pentanoate 
• 119677-63-3 tert-butyl (2S,4R)-5-hydroxy-4-(cyanomethyl)-2-(N-(9-(9-phenylfluorenyl))amino)pentanoate 
• 119595-83-4 tert-butyl (2S,4S)-5-hydroxy-4-(cyanomethyl)-2-(N-(9-(9-phenylfluorenyl))amino)pentanoate 
• 119595-92-5 (2S,4R)-4-(cyanomethyl)-N-(9-(9-phenylfluorenyl))proline tert-butyl ester 
• 119595-89-0 (2S,4S)-4-(cyanomethyl)-N-(9-(9-phenylfluorenyl))proline tert-butyl ester 
• 119595-85-6 tert-butyl (2S,4S)-5-hydroxy-4-propyl-2-(N-(9-(9-phenylfluorenyl))amino)pentanoate 
• 119595-82-3 tert-butyl (2S,4R)-5-hydroxy-4-propyl-2-(N-(9-(9-phenylfluorenyl))amino)pentanoate 
• 119595-91-4 (2S,4S)-4-propyl-N-(9-(9-phenylfluorenyl))proline tert-butyl ester 
• 119595-88-9 (2S,4R)-4-propyl-N-(9-(9-phenylfluorenyl))proline tert-butyl ester 
• 119595-81-2 α-tert-butyl (2S,4R)-5-hydroxy-4-methyl-2-N-(9-(9-phenylfluorenyl)amino)pentanoate 
• 119677-62-2 α-tert-butyl (2S,4S)-5-hydroxy-4-methyl-2-N-(9-(9-phenylfluorenyl)amino)pentanoate 
• 119677-64-4 (2S,4S)-4-methyl-N-(9-(9-phenylfluorenyl))proline tert-butyl ester 
• 119595-87-8 (2S,4R)-4-methyl-N-(9-(9-phenylfluorenyl))proline tert-butyl ester 

Relevant articles and documents

Selective tert-butyl ester deprotection in the presence of acid labile protecting groups with use of ZnBr2

Chemoselective hydrolysis of tert-butyl esters in the presence of other acid-labile groups has been explored by employing α-amino esters and ZnBr2 in DCM. Although N-Boc and N-trityl groups were found to the labile, PhF protected amines were compatible with these Lewis acid deprotection conditions such that a variety of N-(PhF)amino acids were prepared in good yields from their corresponding tert-butyl esters.

Synthese einer neuen nichtnatuerlichen Aminosaeure mit einem Benzodiazepinrest in der Seitenkette und Einbau in ein Tripeptid

-