1198463-59-0

Basic information

• Product Name: (S)-5-[2-(allyloxy)-4-methylpent-4-enylsulfonyl]-1-phenyl-1H-tetrazole:
• Synonyms: (S)-5-[2-(allyloxy)-4-methylpent-4-enylsulfonyl]-1-phenyl-1H-tetrazole:
• CAS NO: 1198463-59-0
• Molecular Weight: 348.426
• Mol File: 1198463-59-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (S)-5-[2-(allyloxy)-4-methylpent-4-enylsulfonyl]-1-phenyl-1H-tetrazole:(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-5-[2-(allyloxy)-4-methylpent-4-enylsulfonyl]-1-phenyl-1H-tetrazole:(1198463-59-0)
• EPA Substance Registry System: (S)-5-[2-(allyloxy)-4-methylpent-4-enylsulfonyl]-1-phenyl-1H-tetrazole:(1198463-59-0)

Safety Data

• Hazardous Substances Data: 1198463-59-0(Hazardous Substances Data)

Upstream product

• 334706-41-1 (S)-2-Allyloxy-4-methyl-pent-4-en-1-ol 
• 372511-49-4 1-((S)-2-Allyloxy-4-methyl-pent-4-enyloxymethyl)-4-methoxy-benzene 
• 1315319-05-1 (S)-1-((4-methoxybenzyl)oxy)-4-methylpent-4-en-2-ol 
• 86-93-1 1-Phenyl-1H-tetrazole-5-thiol 
• 1198463-43-2 (S)-4-methyl-1-(1-phenyl-1H-tetrazol-5-ylthio)pent-4-en-2-ol 
• 1198463-58-9 (S)-5-(oxiran-2-ylmethylthio)-1-phenyl-1H-tetrazole 
• 1198463-44-3 (S)-5-[2-(allyloxy)-4-methylpent-4-enylthio]-1-phenyl-1H-tetrazole 

Downstream Products

• 410095-15-7 (S)-5-[(4-methyl-3,6-dihydro-2H-pyran-2-yl)methylsulfonyl]-1-phenyl-1H-tetrazole 

Relevant articles and documents

Stereoselective synthesis of the C13-C28 subunit of (-)-laulimalide utilizing an α-chlorosulfide intermediate

A stereoselective route to the C13-C28 subunit of (-)-laulimalide is described. l-Tartaric acid is the source of the hydroxy groups at C19 and C20. An α-chlorosulfide is employed as the key intermediate for the creation of the C17-C18 bond and the C16-C17 double bond was introduced using the Mislow-Braverman rearrangement and Hutchin's dexoxygenation with concomitant double bond transposition reaction. The C15 and C23 stereogenic centers were created using catalytic asymmetric reactions. The trisubstituted and trans-disubstituted alkenes were created stereoselectively by taking advantage of ring-closing metathesis and the Julia-Kocienski olefination reaction, respectively. Georg Thieme Verlag Stuttgart, New York.

Evaluating transition-metal-catalyzed transformations for the synthesis of laulimalide

(Chemical Equation Presented) Laulimalide is a structurally unique 20-membered marine macrolide displaying microtubule stabilizing activity similar to that of paclitaxel and the epothilones. The use of atom-economical transformations such as a Rh-catalyze