410095-15-7

Basic information

• Product Name: (S)-5-[(4-methyl-3,6-dihydro-2H-pyran-2-yl)methylsulfonyl]-1-phenyl-1H-tetrazole
• Synonyms: (S)-5-[(4-methyl-3,6-dihydro-2H-pyran-2-yl)methylsulfonyl]-1-phenyl-1H-tetrazole
• CAS NO: 410095-15-7
• Molecular Weight: 320.372
• Mol File: 410095-15-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (S)-5-[(4-methyl-3,6-dihydro-2H-pyran-2-yl)methylsulfonyl]-1-phenyl-1H-tetrazole(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-5-[(4-methyl-3,6-dihydro-2H-pyran-2-yl)methylsulfonyl]-1-phenyl-1H-tetrazole(410095-15-7)
• EPA Substance Registry System: (S)-5-[(4-methyl-3,6-dihydro-2H-pyran-2-yl)methylsulfonyl]-1-phenyl-1H-tetrazole(410095-15-7)

Safety Data

• Hazardous Substances Data: 410095-15-7(Hazardous Substances Data)

Upstream product

• 334706-41-1 (S)-2-Allyloxy-4-methyl-pent-4-en-1-ol 
• 86-93-1 1-Phenyl-1H-tetrazole-5-thiol 
• 289472-96-4 (2S)-(4-methyl-3,6-dihydro-2H-pyran-2-yl)-methanol 
• 302554-94-5 (2S)-2-(4-methoxybenzyloxy)-4-methyl-3,6-dihydro-2H-pyran 
• 372511-49-4 1-((S)-2-Allyloxy-4-methyl-pent-4-enyloxymethyl)-4-methoxy-benzene 
• 1315319-05-1 (S)-1-((4-methoxybenzyl)oxy)-4-methylpent-4-en-2-ol 
• 1198463-44-3 (S)-5-[2-(allyloxy)-4-methylpent-4-enylthio]-1-phenyl-1H-tetrazole 
• 1198463-43-2 (S)-4-methyl-1-(1-phenyl-1H-tetrazol-5-ylthio)pent-4-en-2-ol 
• 1198463-58-9 (S)-5-(oxiran-2-ylmethylthio)-1-phenyl-1H-tetrazole 
• 1198463-59-0 (S)-5-[2-(allyloxy)-4-methylpent-4-enylsulfonyl]-1-phenyl-1H-tetrazole: 
• 302554-87-6 (S)-2-allyloxy-4-methyl-1-trityloxy-4-pentene 
• 66335-71-5 (S)-4-methyl-1-trityloxymethyl-3,6-dihydro-2H-pyran 
• 410095-20-4 5-(6-methyl-3,7-dioxa-bicyclo[4.1.0]hept-4-ylmethanesulfonyl)-1-phenyl-1H-tetrazole 
• 410095-19-1 5-(4-methyl-3,6-dihydro-2H-pyran-2-ylmethylsulfanyl)-1-phenyl-1H-tetrazole 

Downstream Products

• 410095-21-5 (S)-2-[(E)-(3S,4R)-8-(tert-Butyl-diphenyl-silanyloxy)-4-(4-methoxy-benzyloxy)-3-triisopropylsilanyloxy-oct-1-en-6-ynyl]-4-methyl-3,6-dihydro-2H-pyran 
• 1198463-64-7 C₂₅H₃₄O₆ 
• 410095-26-0 {(2S,3S)-3-[(E)-(2R,3S)-2-(4-Methoxy-benzyloxy)-5-((S)-4-methyl-3,6-dihydro-2H-pyran-2-yl)-3-triisopropylsilanyloxy-pent-4-enyl]-oxiranyl}-methanol 
• 410095-25-9 (E)-(5R,6S)-5-(4-Methoxy-benzyloxy)-8-((S)-4-methyl-3,6-dihydro-2H-pyran-2-yl)-6-triisopropylsilanyloxy-oct-7-en-2-yn-1-ol 
• 410095-22-6 (2E,7E)-(5R,6S)-5-(4-Methoxy-benzyloxy)-8-((S)-4-methyl-3,6-dihydro-2H-pyran-2-yl)-6-triisopropylsilanyloxy-octa-2,7-dien-1-ol 

Relevant articles and documents

Stereoselective synthesis of the C13-C28 subunit of (-)-laulimalide utilizing an α-chlorosulfide intermediate

A stereoselective route to the C13-C28 subunit of (-)-laulimalide is described. l-Tartaric acid is the source of the hydroxy groups at C19 and C20. An α-chlorosulfide is employed as the key intermediate for the creation of the C17-C18 bond and the C16-C17 double bond was introduced using the Mislow-Braverman rearrangement and Hutchin's dexoxygenation with concomitant double bond transposition reaction. The C15 and C23 stereogenic centers were created using catalytic asymmetric reactions. The trisubstituted and trans-disubstituted alkenes were created stereoselectively by taking advantage of ring-closing metathesis and the Julia-Kocienski olefination reaction, respectively. Georg Thieme Verlag Stuttgart, New York.

Evaluating transition-metal-catalyzed transformations for the synthesis of laulimalide

(Chemical Equation Presented) Laulimalide is a structurally unique 20-membered marine macrolide displaying microtubule stabilizing activity similar to that of paclitaxel and the epothilones. The use of atom-economical transformations such as a Rh-catalyze