1201-15-6Relevant articles and documents
Nucleophilic Cyclization/Electrophilic Substitution of (2,2-Dialkoxyethyl)ureas: Highly Regioselective Access to Novel 4-(Het)arylimidazolidinones and Benzo[ d[[1,3]diazepinones
Smolobochkin, Andrey V.,Gazizov, Almir S.,Otegen, Nazerke K.,Voronina, Julia K.,Strelnik, Anna G.,Samigullina, Aida I.,Burilov, Alexander R.,Pudovik, Michail A.
, p. 3263 - 3271 (2020)
Imidazolidin-2-one and 1,3-benzodiazepin-2-one scaffolds are structural motifs of many biologically active compounds. Herein, we report a highly regioselective acid-catalyzed intramolecular nucleophilic cyclization/intermolecular electrophilic substitutio
Reactions of resorcinol derivatives with 1-methyl-3-phenylimidazol-2-one as a new method for the synthesis of 5-arylimidazolidin-2-ones
Burilov, Alexander R.,Khakimov, Maxim S.,Gazizov, Almir S.,Pudovik, Mikhail A.,Syakaev, Victor V.,Krivolapov, Dmitry B.,Konovalov, Alexander I.
, p. 54 - 55 (2008/09/18)
Substituted imidazolidin-2-ones have been synthesised by the interaction of imidazol-2-one with 2-methylresorcinol and pyrogallol in a chloroform solution in the presence of trifluoroacetic acid.
Efficient solid-phase synthesis of disubstituted 1,3-dihydro-imidazol-2- ones
Rossé, Gérard,Strickler, Julie,Patek, Marcel
, p. 2167 - 2168 (2007/10/03)
A bromoacetal linker was used to achieve the synthesis of ureas on a solid support. The resulting ureido acetals were treated with TFA and were converted in an intramolecular cyclization via N-acyliminium ion to disubstituted 1,3-dihydro-imidazol-2-ones.