120143-37-5

Basic information

• Product Name: (1S,3S,4R)-menthyl glycinate
• Synonyms: (1S,3S,4R)-menthyl glycinate
• CAS NO: 120143-37-5
• Molecular Weight: 213.32
• Mol File: 120143-37-5.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: (1S,3S,4R)-menthyl glycinate(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,3S,4R)-menthyl glycinate(120143-37-5)
• EPA Substance Registry System: (1S,3S,4R)-menthyl glycinate(120143-37-5)

Safety Data

• Hazardous Substances Data: 120143-37-5(Hazardous Substances Data)

Upstream product

• 7377-98-2 (-)-menthyl chloroacetate 
• 158419-36-4 menthyl Cbz-glycinate 
• 2216-51-5 (-)-menthol 
• 130156-93-3 (2S,5R)-2-isopropyl-5-methyl cyclohexyl-2-azidoacetate 
• 145280-11-1 (1R,2S,5R)-2-(1-methylethyl)-5-methylcyclohexyl 2-<(tert-butoxycarbonyl)amino>acetate 
• 16832-20-5 (1R,2S,5R)-menthol bromoacetate 
• 7377-98-2 (1S,3S,4R)-menthyl chloroacetate 
• 15356-60-2 (1S,2R,5S)-(+)-menthol 

Downstream Products

• 145280-11-1 (1R,2S,5R)-2-(1-methylethyl)-5-methylcyclohexyl 2-<(tert-butoxycarbonyl)amino>acetate 
• 125424-04-6 (S)-2-(Benzhydrylidene-amino)-pent-4-enoic acid (1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyl ester 
• 125424-04-6 (R)-2-(Benzhydrylidene-amino)-pent-4-enoic acid (1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyl ester 
• 125424-00-2 l-menthyl N-(diphenylmethylidene)glycinate 
• 133344-10-2 (1R,3R,4S)-2-Benzenesulfonyl-2-aza-bicyclo[2.2.1]hept-5-ene-3-carboxylic acid (1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyl ester 
• 133344-10-2 (1S,3S,4R)-2-Benzenesulfonyl-2-aza-bicyclo[2.2.1]hept-5-ene-3-carboxylic acid (1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyl ester 
• 133357-66-1 Benzenesulfonylamino-bromo-acetic acid (1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyl ester 
• 125424-02-4 2-[(1R,2R,5R)-2-Hydroxy-2,6,6-trimethyl-bicyclo[3.1.1]hept-(3E)-ylideneamino]-pent-4-enoic acid (1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyl ester 
• 125424-02-4 2-[(1S,2S,5S)-2-Hydroxy-2,6,6-trimethyl-bicyclo[3.1.1]hept-(3E)-ylideneamino]-pent-4-enoic acid (1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyl ester 
• 125424-01-3 2-[(1R,4R)-1,7,7-Trimethyl-bicyclo[2.2.1]hept-(2E)-ylideneamino]-pent-4-enoic acid (1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyl ester 
• 125424-04-6 2-(Benzhydrylidene-amino)-pent-4-enoic acid (1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyl ester 
• 133357-65-0 Benzenesulfonylamino-acetic acid (1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyl ester 
• 125423-98-5 [(1R,2R,5R)-2-Hydroxy-2,6,6-trimethyl-bicyclo[3.1.1]hept-(3E)-ylideneamino]-acetic acid (1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyl ester 
• 125423-98-5 [(1S,2S,5S)-2-Hydroxy-2,6,6-trimethyl-bicyclo[3.1.1]hept-(3E)-ylideneamino]-acetic acid (1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyl ester 

Relevant articles and documents

DERIVATIVES OF MENTHOL AND USES THEREOF

A compound that includes a menthol glycinate. The menthol glycinate includes a menthol connected to a glycine or glycine derivative, via an ester linkage. The groups on the N atom are referred to as R1 and R2, and R1 and R

Synthesis and biological evaluation of menthol-based derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1)

Compound 1 was identified by high throughput screening as a novel PAI-1 inhibitor. Optimization of the B and C-segments of 1 resulted in a series of structurally simplified compounds with improved potency. The synthesis and SAR data of these compounds are presented here.

Facile synthesis of a chiral auxiliary bearing the isocyanide group

A previous study synthesized a chiral auxiliary bearing the isocyanide functionality in six steps and with an oxazoline functionality. This paper discusses the synthesis of a chiral isocyanide possessing the easily cleaved menthoxy group. The synthesis pr