120385-98-0Relevant articles and documents
Kinetics of a Heterogeneous Enzymatic Hydrolysis of a Prochiral Diester
Smith, George B.,Bhupathy, Mahadevan,Dezeny, George C.,Douglas, Alan W.,Lander, Russel J.
, p. 4544 - 4546 (1992)
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A Practical Chemoenzymatic Synthesis Of An LTD4 Antagonist
Hughes, D. L.,Song, Z.,Smith, G. B.,Bergan, J. J.,Dezeny, G. C.,et al.
, p. 865 - 874 (2007/10/02)
Enzymatic asymmetrization of a prochiral diester having 4 bonds between the ester group and prochiral center is the comerstone of a short and efficient synthesis of an LTD4 antagonist.The enzymatic hydrolysis occurs in a heterogeneous slurry, but a kineti
Stereospecific synthesis, assignment of absolute configuration, and biological activity of the enantiomers of 3-[[[3-[2-(7-chloroquinolin-2-yl)-(E)-ethenyl]phenyl][[3-(dimethylami no)-3-oxopropyl]thio]methyl]thio]propionic acid, a potent and specific leuk
Gauthier,Jones,Champion,Charette,Dehaven,Ford-Hutchinson,Hoogsteen,Lord,Masson,Piechuta,Pong,Springer,Therien,Zamboni,Young
, p. 2841 - 2845 (2007/10/02)
The enantiomers of the leukotriene D4 antagonist 3-[[[3-[2-(7-chloroquin-2-yl)-(E)-ethenyl]phenyl][[3-(dimethylamino)- 3-oxopropyl]thio]methyl]thio]propionic acid (L-660,711)(MK-571) have been prepared, their absolute stereochemistry has been a
